DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10949 and CG6683

DIOPT Version :9

Sequence 1:	NP_001286101.1	Gene:	CG10949 / 35310	FlyBaseID:	FBgn0032858	Length:	459	Species:	Drosophila melanogaster
Sequence 2:	NP_648232.1	Gene:	CG6683 / 38970	FlyBaseID:	FBgn0035902	Length:	197	Species:	Drosophila melanogaster

Alignment Length:	316	Identity:	69/316 - (21%)
Similarity:	109/316 - (34%)	Gaps:	130/316 - (41%)

- Green bases have known domain annotations that are detailed below.

  Fly   140 QLIELVKSHPVLYDRHKIRVSKNLAAKN---EAWREISENLNVSEELCYNRWKKLRDRFGREFRS 201
            :|||||:::|.||:| ::|.:...|.|.   |.|..|:.:||.....|.:||..|..:..||...
  Fly     7 RLIELVRANPKLYER-ELRNAPYEAHKKRHPEIWSSIATSLNSEASACVSRWNHLVAKQRRELAK 70

  Fly   202 HQINQSTPITWRYFNDLLFLGRHFRKGVPLVLENIKRRGRPPKAGNPSGKTSKQPEGMVISSGEQ 266
            .:.. .|...|.....|.||..|..   |:...|             ||..|:.    .:.|.::
  Fly    71 EKAG-GTGSDWSLLPHLKFLQHHHH---PINHRN-------------SGDLSRS----TLKSSDE 114

  Fly   267 IWGADYPYSTDNDDLEDDLELAYDEEIEILSEAEQATPYDFILSEATARQDLEPPQQLQVTTTTP 331
            :          ||| ||.|:.|.||::.:...|.                  .||
  Fly   115 V----------NDD-EDPLQEAMDEQLAVAGAAP------------------APP---------- 140

  Fly   332 ATSEEIIHTIARVNPVVEESSSLPGDSVPSAAISDKLLTTVIANMETVLQQSRELQAQIHHEQEQ 396
                        .||                           |:...|.|..:.::|
  Fly   141 ------------TNP---------------------------AHATPVAQAEKRIEA-------- 158

  Fly   397 EREQRSTQPANSLLAKAQMLLDGLSPSERASAERKIVQFLCQCQIKALDGEEIEDV 452
                               ||:||..:.|..||::|:.:||:|.::||:.|:|:|:
  Fly   159 -------------------LLEGLGEANRIKAEKRILAYLCKCNLRALNDEQIDDI 195

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10949	NP_001286101.1	MADF	5..91	CDD:214738
CG10949	NP_001286101.1	MADF	140..226	CDD:214738	29/88 (33%)
CG6683	NP_648232.1	MADF	7..94	CDD:214738	29/88 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0009996
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR12243
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	3.010