DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10949 and Amyrel

DIOPT Version :9

Sequence 1:	NP_001286101.1	Gene:	CG10949 / 35310	FlyBaseID:	FBgn0032858	Length:	459	Species:	Drosophila melanogaster
Sequence 2:	NP_477262.1	Gene:	Amyrel / 36863	FlyBaseID:	FBgn0020506	Length:	493	Species:	Drosophila melanogaster

Alignment Length:	228	Identity:	47/228 - (20%)
Similarity:	75/228 - (32%)	Gaps:	66/228 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   131 DSQDDLLNEQLIELVKSHPVLYDRHKIRVSKNLAAKNEAWREIS------ENLNVSEELCYNR-- 187
            |...|.:..:|||.: .|.:.......||.   |||:.|..::.      .|||:.....:|.
  Fly   179 DQSSDWVRSKLIEFL-DHLIELGVAGFRVD---AAKHMASEDLEYIYSSLSNLNIDHGFPHNSRP 239

  Fly   188 --WKKLRDRFGRE--FRSHQINQSTPITWRYFNDLLFLGRHFRKGVPLVLENIKRRGRPPKAGNP 248
              ::::.|. |.|  .|....:......:|:..:   :|..||                   ||.
  Fly   240 FIFQEVIDH-GHETVSRDEYKDLGAVTEFRFSEE---IGNAFR-------------------GNN 281

  Fly   249 SGKTSKQPEGMVISSGEQIWGADYPY--------STDNDDLEDD----LELAYDEEIEILSEAEQ 301
            :.|..            |.||.|:.:        ..||.|.:.|    |......:.::.:....
  Fly   282 ALKWL------------QSWGTDWGFLPSGQALTFVDNHDNQRDAGAVLNYKSPRQYKMATAFHL 334

  Fly   302 ATPYDF---ILSEATARQDLEPPQQLQVTTTTP 331
            |.||..   :.|.|....|..|||..|....:|
  Fly   335 AYPYGISRVMSSFAFDDHDTPPPQDAQERIISP 367

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10949	NP_001286101.1	MADF	5..91	CDD:214738
CG10949	NP_001286101.1	MADF	140..226	CDD:214738	20/97 (21%)
Amyrel	NP_477262.1	AmyAc_bac_euk_AmyA	29..398	CDD:200456	47/228 (21%)
Amyrel	NP_477262.1	Aamy_C	404..492	CDD:214749
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0366
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900