DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10949 and Mal-A8

DIOPT Version :9

Sequence 1:	NP_001286101.1	Gene:	CG10949 / 35310	FlyBaseID:	FBgn0032858	Length:	459	Species:	Drosophila melanogaster
Sequence 2:	NP_610384.1	Gene:	Mal-A8 / 35830	FlyBaseID:	FBgn0033297	Length:	588	Species:	Drosophila melanogaster

Alignment Length:	247	Identity:	42/247 - (17%)
Similarity:	80/247 - (32%)	Gaps:	85/247 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    72 DEPTYWDMFPRLLFLKDHYKQGLARNESLD---GMRFEPRERKKRTKVDMEQERRRKDEEEEDSQ 133
            |...::|:.|....|:| ::..:.|.:.||   .:.|.|......::..::..:|.|..|:
  Fly    92 DISDFFDIQPEYGTLED-FRTLIKRAKELDLKIVLDFVPNHSSNESEWFLKSVKREKGYED---- 151

  Fly   134 DDLLNEQLIELVKSHPVLYDRHKIRVSKNLAA-----------KNEAWREISENLNVSEELCYNR 187
                             .|..|..:|:.....           :..||                .
  Fly   152 -----------------YYVWHDGKVNSTTGKREPPTNWLQYFRGSAW----------------E 183

  Fly   188 WKKLRDRFGREFRSHQINQSTPITWRYFNDLLFLGRHFRKGVPLVLENIKRRGR----------- 241
            |.::|    :::..||.....|       ||     ::|.  |||:|.:||..|
  Fly   184 WNEVR----QQYYLHQFAVQQP-------DL-----NYRN--PLVVEQMKRVLRYWLNEGVSGFR 230

  Fly   242 ----PPKAGNPSGKTSKQPEGMVISSGEQIWGADYPYSTDNDDLEDDLELAY 289
                ||..........:.|:.:|..:.|.....||..:|..::..:.:::.|
  Fly   231 CDALPPLFEVVPDSDGQFPDEVVSGATEDKEDRDYLTTTYIENQPETIDMVY 282

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10949	NP_001286101.1	MADF	5..91	CDD:214738	5/18 (28%)
CG10949	NP_001286101.1	MADF	140..226	CDD:214738	12/96 (13%)
Mal-A8	NP_610384.1	AmyAc_maltase	30..506	CDD:200467	42/247 (17%)
		trehalose_treC	33..585	CDD:274115	42/247 (17%)
		Malt_amylase_C	487..585	CDD:295440
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0366
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900