DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10949 and madf-4

DIOPT Version :9

Sequence 1:	NP_001286101.1	Gene:	CG10949 / 35310	FlyBaseID:	FBgn0032858	Length:	459	Species:	Drosophila melanogaster
Sequence 2:	NP_505565.3	Gene:	madf-4 / 179386	WormBaseID:	WBGene00011575	Length:	329	Species:	Caenorhabditis elegans

Alignment Length:	323	Identity:	71/323 - (21%)
Similarity:	122/323 - (37%)	Gaps:	98/323 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   124 RKDEEEEDSQDDLLNEQLIELVKSHPVLYDR----HKIRVSKNLAAKNEAWREISENLNVSEELC 184
            |.|....|..:|.....||:.|:.:|.:|:|    ||:     ...|:|.|:.|      |.|:.
Worm     5 RADSPNHDPLEDDFTLALIDSVQRNPCVYNRYDPLHKV-----TDYKHEIWKLI------SIEIG 58

  Fly   185 YN--------RWKKLRDRFGREFRSHQINQSTPIT-----WRYFNDLLFLGRHFRKGVPLVLENI 236
            |:        :||.:||::.|  ...|..|..||.     :.|::.:.||..:...      .|.
Worm    59 YDGQPVELERKWKHMRDKYVR--LRKQDKQKAPIKKTNKWYNYYHKMSFLDPYVEH------RNR 115

  Fly   237 KRRGRPPKAGNP-------------SGKTSKQPEGMVISSGEQIWGADYPYSTDND--------- 279
            ||:.....:..|             |.|...:||.::.|:..   |.:.|::|.:.
Worm   116 KRQKDYLNSNTPDFLDDDTAFLDGLSVKEMLKPESLLTSNDA---GYNSPHTTSSSSSSGSNNNG 177

  Fly   280 --------DLEDD---LELAYDEEIEILSEAEQATPY------DFILSEATARQDLEPPQQLQVT 327
                    |:|||   |.|.||:.:...:|.|:...:      |.:.|  |....:|   :|..|
Worm   178 RFLDSPTIDIEDDKKNLALIYDKFVANQTENEKNHRFSNKHGKDLLFS--TTNTLIE---KLATT 237

  Fly   328 TTTPATSEEIIHTIARVNPVVEESSSLPGDSVPSAAISDKLLTTVIANMETVLQQSRELQAQI 390
            :|.|::|              .:...:|...:||:....: ..|.|..:|.:|.:..|.|..:
Worm   238 STAPSSS--------------RKRKPIPVQILPSSPPPQE-KNTKIELLEDILNEPNEDQVSL 285

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10949	NP_001286101.1	MADF	5..91	CDD:214738
CG10949	NP_001286101.1	MADF	140..226	CDD:214738	27/102 (26%)
madf-4	NP_505565.3	MADF	22..111	CDD:214738	27/101 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm14087
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910