DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10949 and madf-2

DIOPT Version :9

Sequence 1:	NP_001286101.1	Gene:	CG10949 / 35310	FlyBaseID:	FBgn0032858	Length:	459	Species:	Drosophila melanogaster
Sequence 2:	NP_492896.1	Gene:	madf-2 / 173019	WormBaseID:	WBGene00009461	Length:	290	Species:	Caenorhabditis elegans

Alignment Length:	264	Identity:	60/264 - (22%)
Similarity:	95/264 - (35%)	Gaps:	76/264 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   141 LIELVKSHPVLYDRHKIRVSKNLAAKNEAWREISENLNVSEEL-----C---YNRWKKLRDRFGR 197
            ||..:::.||::|::....|.....|....||::..||...::     |   .::||.|:|.|.|
Worm    12 LINAIRNRPVIWDKNYFGESNYRTLKTSCLREVTSELNSMFQMPIKFTCEDVRSQWKNLKDTFVR 76

  Fly   198 EFR-----SHQINQSTPITWRYFNDLLFLGRHFRKGVPLVLE-------NIKRRGR--------- 241
            :.|     .:..:.....||:::..|.||.....|.:....|       |....|:
Worm    77 KLRWVHEGKYMEDAMKEPTWKFYRMLTFLDEKEAKRLGDTCEHTYELAPNSTSCGQRAQISYEPT 141

  Fly   242 --------------PPKAGNPS-------GKTSKQPE-----GMVISSGEQIWGADY-PYSTDN- 278
                          ||:....|       ...|.:|:     ..|.||.....|..| |..:.|
Worm   142 STEEKMFQMFNNQPPPQLSQQSMIDSSQIATCSNEPKMTSSSTFVTSSTSLKRGVHYSPTRSPNG 206

  Fly   279 --DDLEDDLELAYDEEIEILSEAEQATPYDFILSEATARQDLEPPQQLQVTTTTP-ATSEEIIHT 340
              ..||::||   ||:       ||..      .:.:.|:.:...|.:||.||.| |..:|..|.
Worm   207 SSSGLEEELE---DED-------EQPG------RKKSCRRQVSNIQPMQVITTPPVAHQDEFDHF 255

  Fly   341 IARV 344
            .|.|
Worm   256 GAMV 259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10949	NP_001286101.1	MADF	5..91	CDD:214738
CG10949	NP_001286101.1	MADF	140..226	CDD:214738	24/97 (25%)
madf-2	NP_492896.1	MADF	11..107	CDD:214738	24/94 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12243
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100