DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10949 and Slc3a2

DIOPT Version :9

Sequence 1:	NP_001286101.1	Gene:	CG10949 / 35310	FlyBaseID:	FBgn0032858	Length:	459	Species:	Drosophila melanogaster
Sequence 2:	NP_001154885.1	Gene:	Slc3a2 / 17254	MGIID:	96955	Length:	565	Species:	Mus musculus

Alignment Length:	160	Identity:	38/160 - (23%)
Similarity:	63/160 - (39%)	Gaps:	45/160 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   159 VSKNLAAKNEAWREISENLNVSEELCYNRWKKLRDRFGREFRS------HQINQSTPITWRYFND 217
            ||.|:..|.:         |........::::|.|..|:| ||      |.::.|.        |
Mouse   435 VSLNMTVKGQ---------NEDPGSLLTQFRRLSDLRGKE-RSLLHGDFHALSSSP--------D 481

  Fly   218 LLFLGRHFRKGVP-LVLENIKRRGRPPKAGNPSGKTSKQPEGMVISSGEQIWGADYPYSTDN--D 279
            |....||:.:... ||:.|.:..||..:.|     .|..|.|:.:.:..::.     .|||:  .
Mouse   482 LFSYIRHWDQNERYLVVLNFRDSGRSARLG-----ASNLPAGISLPASAKLL-----LSTDSARQ 536

  Fly   280 DLEDDLELAYDEEIEILSEAEQATPYDFIL 309
            ..|:|..|    ::|.||    ..||:.:|
Mouse   537 SREEDTSL----KLENLS----LNPYEGLL 558

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10949	NP_001286101.1	MADF	5..91	CDD:214738
CG10949	NP_001286101.1	MADF	140..226	CDD:214738	17/72 (24%)
Slc3a2	NP_001154885.1	SLC3A2_N	85..156	CDD:292647
		AmyAc_family	139..468	CDD:298606	10/42 (24%)
		AmyA	169..513	CDD:223443	23/100 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0366
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900