DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10949 and si:zfos-128g4.1

DIOPT Version :9

Sequence 1:	NP_001286101.1	Gene:	CG10949 / 35310	FlyBaseID:	FBgn0032858	Length:	459	Species:	Drosophila melanogaster
Sequence 2:	XP_002661969.1	Gene:	si:zfos-128g4.1 / 100334256	ZFINID:	ZDB-GENE-141212-382	Length:	248	Species:	Danio rerio

Alignment Length:	311	Identity:	67/311 - (21%)
Similarity:	118/311 - (37%)	Gaps:	76/311 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   138 NEQLIELVKSHPVLYD--RHKIRVSKNLAAKNEAWREISENLNVSEELCYNRWKKLRDRFGREFR 200
            :|:||:.|.:.||||:  .|..|.::.   :.:||||::.::.:|...|..|||.:|||:.||.|
Zfish     6 SEKLIQTVYAFPVLYNVSLHDYRSTER---RVKAWREVAASVGLSVVECKRRWKTIRDRYIRERR 67

  Fly   201 SHQINQSTP----ITWRYFNDLLFLGRHFRKGVPLVLENIKRRGRPPKAGNPSGKTSKQPEGMVI 261
            ..::.:...    ..|.:...|.||..|.||           |.||..|..|..:..::.....
Zfish    68 LCKLKKDLGGRRLHYWPHRESLAFLDAHIRK-----------RRRPSGAQGPEEEQQEEHSSAA- 120

  Fly   262 SSGEQIWGADYPYSTDNDDLEDDLELAYDEEIEILSEAEQATPYDFILSEATARQDLEPPQQLQV 326
                               |::|.|...:|.::..|.. ..:|....:..|      .||.||:
Zfish   121 -------------------LQEDKECVSEECVDSGSRL-AVSPLPVSIMSA------PPPPQLK- 158

  Fly   327 TTTTPATSEEIIHTIARVNPVVEESSSLPGDSVPSAAISDKLLTTVIANMETVLQQSRELQAQIH 391
                         .:.:|:|::            .||:...|....:.:..|....:..|...:
Zfish   159 -------------AVPQVSPLL------------LAALPPGLKVAPVCSSATGSASAGPLNVPL- 197

  Fly   392 HEQEQEREQRSTQPANSLLAKAQMLLDGLSPSERASAERKIVQFLCQCQIK 442
              :||:|...:.......|......|..|:|.:||:.:.:|.|.:...:.|
Zfish   198 --EEQQRADGALDEDQLFLLSYVPALKRLTPQKRAAVKMQIQQIMFNAEFK 246

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10949	NP_001286101.1	MADF	5..91	CDD:214738
CG10949	NP_001286101.1	MADF	140..226	CDD:214738	29/91 (32%)
si:zfos-128g4.1	XP_002661969.1	MADF	8..97	CDD:214738	29/91 (32%)
si:zfos-128g4.1	XP_002661969.1	BESS	208..242	CDD:281011	8/33 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1634040at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920