Protein Alignment CG10947 and VCPKMT

DIOPT Version :10

• Sequence 1: NP_610031.1
• Gene: CG10947 / 35309
• FlyBaseID: FBgn0032857
• Length: 404
• Species: Drosophila melanogaster
• Sequence 2: XP_005268117.1
• Gene: VCPKMT / 79609
• HGNCID: 20352
• Length: 272
• Species: Homo sapiens
• Alignment Length: 241
• Identity: 61/241 - (25%)
• Similarity: 99/241 - (41%)
• Gaps: 68/241 - (28%)

  Fly   193 ERQLTASDLMGFNNTGNIC-VWPSEEALTALVLS---EVASYRG--------KWILELGGGFTSL 245
            :|..|...|..:::.|..| ||.:     |:|||   |...:.|        :.:||||.| |..
Human    22 KRDGTVLRLQQYSSGGVGCVVWDA-----AIVLSKYLETPEFSGDGAHALSRRSVLELGSG-TGA 80

  Fly   246 AGLMLAKYATPYAVHLTDGNEISVENVRKTVCLNE--LSCYTKCSVLKWQEKSARSQAEQAKFDF 308
            .|||.|.......|  ||..|:. :.::..:.:|:  ::...:..||||.|:   .:...:..||
Human    81 VGLMAATLGADVVV--TDLEELQ-DLLKMNINMNKHLVTGSVQAKVLKWGEE---IEGFPSPPDF 139

  Fly   309 ILCADCLFFDEARSALVDTIWYYLAPEGSALIMAPRRGRTLSVFQDECV-------ARGFRVELA 366
            ||.|||::::|:...|:.|:                  :.:|.| :.|:       ..|...|:.
Human   140 ILMADCIYYEESLEPLLKTL------------------KDISGF-ETCIICCYEQRTMGKNPEIE 185

  Fly   367 TRYNETIWQRHLQL----------KADSALYDEDLHYPLLLRLCKS 402
            .:|.|.     |||          |.|.....||:|. :.:|..||
Human   186 KKYFEL-----LQLDFDFEKIPLEKHDEEYRSEDIHI-IYIRKKKS 225

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10947	NP_610031.1	AdoMet_MTases	199..352	CDD:473071	42/166 (25%)
VCPKMT	XP_005268117.1	Methyltransf_16	22..195	CDD:313513	52/208 (25%)