DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt37A1 and UGT85A7

DIOPT Version :9

Sequence 1:	NP_523607.2	Gene:	Ugt37A1 / 35307	FlyBaseID:	FBgn0026756	Length:	522	Species:	Drosophila melanogaster
Sequence 2:	NP_173652.1	Gene:	UGT85A7 / 838841	AraportID:	AT1G22340	Length:	487	Species:	Arabidopsis thaliana

Alignment Length:	559	Identity:	108/559 - (19%)
Similarity:	197/559 - (35%)	Gaps:	177/559 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 LIYGAQGANILGLFPSLSPSHLIISMSVAKILAEQGHNVTVVTVLE-----------------PT 65
            :::.||..::: ..|..:..|:...:.|||:|..:|.:||.|..|.                 |:
plant     5 VVHNAQKPHVV-CVPYPAQGHINPMLKVAKLLYAKGFHVTFVNTLYNHNRLLRSRGPNALDGFPS 68

  Fly    66 ITHKNI-------------NLVTVPMTKE--------EIKQR-------------------SETI 90
            ...::|             :..||.|:.|        ||.:|                   |.|:
plant    69 FRFESIPDGLPETDGDRTQHTPTVCMSIEKNCLAPFKEILRRINDKDDVPPVSCIVSDGVMSFTL 133

  Fly    91 GAKQK---------NTSSNRFISILNMSGQMDSMLRKMADVLKDQRVKELYLNKDNHFDLVISGY 146
            .|.::         ..|:..|::||:..    ..:.|.....||    |.|::|: |.|.||
plant   134 DAAEELGVPEVIFWTNSACGFMTILHFY----LFIEKGLSPFKD----ESYMSKE-HLDTVI--- 186

  Fly   147 FMNDY--QLGFARKVNAPVVVLAPSPPSQMLNSLIGNPHDKVEKEKGM------TFGQRLDSYIS 203
               |:  .:...|..:.|..:...:|.:.|||.||    .:||:.|..      ||.:.....|.
plant   187 ---DWIPSMKNLRLKDIPSYIRTTNPDNIMLNFLI----REVERSKRASAIILNTFDELEHDVIQ 244

  Fly   204 SL------------LYGIFLRQIDQRNR--QYYNEIFGDDPTMPEYTDILRNTSLVFFCSHAASE 254
            |:            |:.:...:|::.:.  |....::.::....::.|.....|::|
plant   245 SMQSILPPVYSIGPLHLLVKEEINEASEIGQMGLNLWREEMECLDWLDTKTPNSVLF-------- 301

  Fly   255 GPIRPSVPAAIEIGGIQIKDKPDPLPKNLEKFLGNATHGAILLSLGSNVQGSHIKADTVKKIFSV 319
                      :..|.|.:..     .|.||:|...                  :.|...:.::.:
plant   302 ----------VNFGCITVMS-----AKQLEEFAWG------------------LAASRKEFLWVI 333

  Fly   320 LSNL---KQRVIWKWDDLDKTPGKSDNILYSRWLPQDDILAHPSVKLFINHAGKGGISEAQYHGK 381
            ..||   :..|:...:.|.:|   .|..:.:.|.||:.:|:||::..|:.|.|.....|:...|.
plant   334 RPNLVVGEAMVVLPQEFLAET---IDRRMLASWCPQEKVLSHPAIGGFLTHCGWNSTLESLAGGV 395

  Fly   382 PMLSLPVFGDQPGNAHAMVKS-GFGLTLSLLTLEEEPFRAAVLEILSNPKYSQRVVKFSSLYRDR 445
            ||:..|.|.:||.|....... |.|:.:. ..::.|.....|.|::...|..:
plant   396 PMICWPCFSEQPTNCKFCCDEWGVGIEIG-KDVKREEVETVVRELMDGEKGKK------------ 447

  Fly   446 PASARESLIFW---TEYVIRH-HGAAHLQ-SPLVHMDFI 479
               .||....|   .|...|: ||::.:. ..|:|..|:
plant   448 ---LREKAEEWRRLAEEATRYKHGSSVMNLETLIHKVFL 483

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A1	NP_523607.2	GT1_Gtf-like	25..456	CDD:340817	98/522 (19%)
UGT85A7	NP_173652.1	Glycosyltransferase_GTB-type	12..481	CDD:385653	105/548 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000