Protein Alignment Ugt37A1 and ugt1b4

DIOPT Version :10

• Sequence 1: NP_523607.2
• Gene: Ugt37A1 / 35307
• FlyBaseID: FBgn0026756
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: NP_001166239.2
• Gene: ugt1b4 / 795050
• ZFINID: ZDB-GENE-080227-13
• Length: 533
• Species: Danio rerio
• Alignment Length: 519
• Identity: 148/519 - (28%)
• Similarity: 245/519 - (47%)
• Gaps: 65/519 - (12%)

  Fly    37 SHLIISMSVAKILAEQGHNVTVVTV-----LEP---TITHK--------NINLVTVPMTKEEIKQ 85
            ||.....:||:.:..:||.|.||..     |.|   .||.|        .||.:.|....|
Zfish    45 SHWTGVKAVAEEMGRRGHTVIVVIPEISMRLGPGKHYITKKFPVQYKQDLINQIMVEHVNE---- 105

  Fly    86 RSETIGAKQKNTSSNRFISILNMSGQ-MDSMLRKMADVLKDQRVKELYLNKDNHFDLVISGYFMN 149
                :.|.:::.... ..||:...|: :|..:.....:.::|.:.|..  :|.:||.|::...|
Zfish   106 ----VAASEQSLLKT-VTSIMYRFGKIIDHFISTSESLFQEQELIEFL--RDQNFDAVLTNPAM- 162

  Fly   150 DYQLG--FARKVNAPVVVL------------APSPPSQMLNSLIGNPHDKVEKEKGMTFGQRLDS 200
              .:|  .|..::.|.|.:            .|:|||.:       |....:....|||.:|:.:
Zfish   163 --PMGAILAYNLSVPAVYMLRGIMCESKATACPNPPSYI-------PRFFTQISDRMTFSERVIN 218

  Fly   201 YISSLLYGIFLRQIDQRNRQYYNEIFGDDPTMPEYTDILRNTSLVFFCSHAASEGPIRPSVPAAI 265
            .:.|||..:..|.:.....:..::....|.::   |:||...::.........|.| :|.:|..|
Zfish   219 TLVSLLEPLMCRLMLGSFEEMTSKFLHRDVSI---TEILSTAAVWLMRYDFTLEFP-KPLMPNMI 279

  Fly   266 EIGGIQIKDKPDPLPKNLEKFL-GNATHGAILLSLGSNVQG-SHIKADTVKKIFSVLSNLKQRVI 328
            .||||..:.| :||.|.:|:|: |:..||.::.||||.|.. ...|||...|.||:   :.|||:
Zfish   280 TIGGINCEVK-NPLTKEVEEFVNGSGEHGIVVFSLGSLVSSMPKEKADIFFKAFSM---IPQRVL 340

  Fly   329 WKWDDLDKTPGK-SDNILYSRWLPQDDILAHPSVKLFINHAGKGGISEAQYHGKPMLSLPVFGDQ 392
            |::  ..:.|.. .:|:...:||||:|:|.||..:.||.|.|..||.|...||.||:.||:||||
Zfish   341 WRY--TGEIPNNVPENVKLMKWLPQNDLLGHPKARAFITHGGTHGIYEGICHGVPMVMLPLFGDQ 403

  Fly   393 PGNAHAMVKSGFGLTLSLLTLEEEPFRAAVLEILSNPKYSQRVVKFSSLYRDRPASARESLIFWT 457
            ..|.|.:...|.|:.||:..:..|....|:..:::|..|.|::.|.|:::.|||....:..:|||
Zfish   404 ADNVHRVATRGVGVILSIHDITVETLLDALNSVINNSSYKQKMQKLSAIHNDRPIQPLDLAVFWT 468

  Fly   458 EYVIRHHGAAHLQSPLVHMDFIAANNLDIYALIGAISIGLLLMLKKVVQITCRRLRTKLNKVKK 521
            |:|:||.||.||:.....::::..::||:...:..|.:.:.|.:.|...:..||...|..|.|:
Zfish   469 EFVMRHKGADHLRPAAHELNWLQYHSLDVIGFMLLIVLIVTLAMLKCCSLCWRRCCRKTQKRKE 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A1	NP_523607.2	GT1_Gtf-like	25..456	CDD:340817	127/452 (28%)
ugt1b4	NP_001166239.2	UDPGT	35..529	CDD:278624	146/514 (28%)