Protein Alignment Ugt37A1 and ugt2a5

DIOPT Version :10

• Sequence 1: NP_523607.2
• Gene: Ugt37A1 / 35307
• FlyBaseID: FBgn0026756
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: NP_001070111.2
• Gene: ugt2a5 / 767705
• ZFINID: ZDB-GENE-060929-796
• Length: 532
• Species: Danio rerio
• Alignment Length: 524
• Identity: 142/524 - (27%)
• Similarity: 242/524 - (46%)
• Gaps: 66/524 - (12%)

  Fly    37 SHLIISMSVAKILAEQGHNVTV-VTVLEPTITHK-----NINLVTVPMTKEE--------IKQRS 87
            ||......|.:.|.::.|:||| |....||:.|.     ..::..|.|.|||        |...:
Zfish    31 SHWHNMRPVIEALVDKNHSVTVLVGSSSPTVPHTQKERFEYHVFKVNMEKEEADAAMRDMIHLFT 95

  Fly    88 ETIGAKQKNTSSNRFISILNMSGQM---DSMLRKMADV--LKDQRVKELYLNKDNHFDLVISGYF 147
            ....||.:    ..|:....||..:   |...|.:.||  ||..|        |:::|::.|...
Zfish    96 NDTAAKYE----GEFVMWKVMSKFVEFGDVYFRGLFDVGLLKTLR--------DSNYDVLFSDPM 148

  Fly   148 MNDYQLGFARKVNAPVVV---------------LAPSPPSQM-LNSLIGNPHDKVEKEKGMTFGQ 196
            |....| .|:|:|.|.|:               ..|:|||.: ..:|..:..|:      |:|.:
Zfish   149 MPFSDL-MAQKLNIPQVISMRATFAYAAERLCGQMPAPPSYVPAVALTDHLTDR------MSFME 206

  Fly   197 RLDSYISSLLYGIFLRQIDQRNRQ-YYNEIFGDDPTMPEYTDILRNTSLVFFCSHAASEGPIRPS 260
            |:::.:..:::.|....:...... ||:||.|...||.|   .:....:....::...|.| ||.
Zfish   207 RVENMLLYIVHSIAFPLVATFTFDGYYSEILGKPTTMCE---TMGKVDICLIRTYWDFEYP-RPF 267

  Fly   261 VPAAIEIGGIQIKDKPDPLPKNLEKFL-GNATHGAILLSLGSNVQGSHIKADTVKKIFSVLSNLK 324
            .|....:||:..| ...||.|.||:|: .:..||.::.||||.::  ::.::....|.:.|..:.
Zfish   268 PPNFKFVGGLHCK-PAKPLSKELEEFVQSSGDHGVVVFSLGSMIK--NLTSERANTIAAALGQIP 329

  Fly   325 QRVIWKWDDLDKTPGK-SDNILYSRWLPQDDILAHPSVKLFINHAGKGGISEAQYHGKPMLSLPV 388
            |:|:|::.  .|||.. :.|.....|:||:|:|.||..|.||.|.|..|:.||.|||.||:.||:
Zfish   330 QKVVWRYS--GKTPETLAPNTKIYDWIPQNDLLGHPKTKAFITHGGTNGLYEAIYHGVPMVGLPL 392

  Fly   389 FGDQPGNAHAMVKSGFGLTLSLLTLEEEPFRAAVLEILSNPKYSQRVVKFSSLYRDRPASARESL 453
            |||||.|...:...|..:.|.:.|:..:....|:..:::||.|.:.:::.|.::.|:|....:..
Zfish   393 FGDQPDNLLHIKTKGAAVVLDIHTMGSKDLVDALKAVVNNPSYKESIMRLSRIHHDQPMKPLDQA 457

  Fly   454 IFWTEYVIRHHGAAHLQSPLVHMDFIAANNLDIYALIGAISIGLLLMLKKVVQITCRRLRTKLNK 518
            ::|.|:|:|:.||.||:.....:.:...:.||:.|.:.:|:..:..:..|......||...|...
Zfish   458 VYWIEFVMRNKGAKHLRVQAHELSWYQYHCLDVAAFLLSITALITFLWVKACCFLFRRCVRKTRP 522

  Fly   519 VKKQ 522
            .:|:
Zfish   523 ERKR 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A1	NP_523607.2	GT1_Gtf-like	25..456	CDD:340817	125/456 (27%)
ugt2a5	NP_001070111.2	UDPGT	21..519	CDD:278624	140/515 (27%)