Protein Alignment Ugt37A1 and ugt5c2

DIOPT Version :10

• Sequence 1: NP_523607.2
• Gene: Ugt37A1 / 35307
• FlyBaseID: FBgn0026756
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: NP_001038851.1
• Gene: ugt5c2 / 751669
• ZFINID: ZDB-GENE-060825-206
• Length: 552
• Species: Danio rerio
• Alignment Length: 555
• Identity: 156/555 - (28%)
• Similarity: 257/555 - (46%)
• Gaps: 92/555 - (16%)

  Fly    17 LLIYGA--QGANILGLFPSLSPSHLIISMSVAKILAEQGHNVTVVTVLEPTITHKN---INLVTV 76
            :.|:|:  .|..|  |...|..||.:....:.|.|..|||.|.|:.........:|   .:.:|:
Zfish    39 ITIFGSLCDGGKI--LVAPLEGSHWVNMDILIKALHGQGHTVDVIRNANSWFIKENSTYYDTITI 101

  Fly    77 PMTK---EE---------IKQRSETIGAKQKNTSSNRFISILNMSGQMDSMLRK--------MAD 121
            |.||   ||         ||...|          ...::||:.:...:...::|        :.:
Zfish   102 PNTKGWDEEFAADFVYKMIKYEKE----------KGSWLSIVRLYLNVFDAVKKTHEMVCQLITN 156

  Fly   122 VLKDQRVKELYLNKDNHFDLVISGYFMNDYQLG----FARKVNAPVVV-------------LAPS 169
            :|..:.:.:: || :..:||:::     |...|    .|.|:..|:|.             :|||
Zfish   157 ILDSEEILKM-LN-EKQYDLMLT-----DPVWGTGIILAHKLKLPMVYNVRWTTTGEGHFDIAPS 214

  Fly   170 PPSQMLNSLIGNPHDKVEKEKGMTFGQRLDSYISSLLYGIFLRQIDQRNRQ-----YYNEIFGDD 229
            |.|.:..:..||. |:      |:|.|||.:|...||..:.|...:.:..|     |:.
Zfish   215 PMSYIPITGSGNT-DR------MSFFQRLKNYFFYLLLDLQLSHFNVKQYQAICDKYFT------ 266

  Fly   230 PTMPEYTDILRNTSLVFFCSHAASEGPIRPSVPAAIEIGGIQIKDKPDPLPKNLEKFL-GNATHG 293
             :...:.::|:...|.........|.| ||::|..|.|||.|. ....|||.:||.|: .:..||
Zfish   267 -SRVNFHELLQGADLWLMRVDFVFEFP-RPTMPNIIYIGGFQC-PPAKPLPHDLEDFMQSSGDHG 328

  Fly   294 AILLSLGSNVQGSHIKADTVKKIFSVLSNLKQRVIWKWDDLDKTPGK-SDNILYSRWLPQDDILA 357
            .|::||||.:  .::..:...:|.:..:.|.|:|||::  ..|.|.. |:|.|...|:||.|:|.
Zfish   329 VIVMSLGSLI--GNLPENVTAEIAAAFARLPQKVIWRY--TGKKPSTLSNNTLMVDWMPQKDLLG 389

  Fly   358 HPSVKLFINHAGKGGISEAQYHGKPMLSLPVFGDQPGNAHAMVKSGFGLTLSLLTLEEEPFRAAV 422
            ||..|:||:|.|..|:.||.|||.|::.:|.|.||..|...:...|....||:..|.|....||:
Zfish   390 HPKTKVFISHGGTNGVLEALYHGVPVIGIPFFFDQYDNLIRLQARGGAKLLSIADLGENTLHAAI 454

  Fly   423 LEILSNPKYSQRVVKFSSLYRDRPASARESLIFWTEYVIRHHGAAHLQSPLVHMDFIAANNLDIY 487
            .|:::.|.|...:.|.|.|::|:|....:|.|||.|:|:||.|||||::....|.:.:.:::|:.
Zfish   455 QEVINEPSYRLNMHKLSHLHKDKPVKPLDSAIFWIEFVMRHKGAAHLRTESYKMPWYSYHSVDVV 519

  Fly   488 ALIGAISIGLLLMLKKVVQITCRRLRTKLNKVKKQ 522
            ..:.|:    :|:|...:.:|.|.|..|....|::
Zfish   520 VTLFAV----VLILTYCIFVTVRYLCVKCCSQKRK 550

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A1	NP_523607.2	GT1_Gtf-like	25..456	CDD:340817	132/477 (28%)
ugt5c2	NP_001038851.1	UDPGT	49..551	CDD:278624	153/545 (28%)