Protein Alignment Ugt37A1 and UGT8

DIOPT Version :9

• Sequence 1: NP_523607.2
• Gene: Ugt37A1 / 35307
• FlyBaseID: FBgn0026756
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: NP_001121646.2
• Gene: UGT8 / 7368
• HGNCID: 12555
• Length: 541
• Species: Homo sapiens
• Alignment Length: 558
• Identity: 157/558 - (28%)
• Similarity: 265/558 - (47%)
• Gaps: 89/558 - (15%)

  Fly     6 KSYFVIVLALTLLIYGAQGANILGLFPSLSPSHLIISMSVAKILAEQGHNVTVVTVLE-----PT 65
            |||....:.|...:..|:.|.|:.:.|.:..||:.|..::|..|.|:||: ||..:.|     |:
Human     2 KSYTPYFILLWSAVGIAKAAKIIIVPPIMFESHMYIFKTLASALHERGHH-TVFLLSEGRDIAPS 65

  Fly    66 ITHKNINLVTVP-----MTKEEIKQRSETIGAKQKNTSSNRFISILNMSGQMDSMLRKMADVLKD 125
               .:.:|...|     .|.:...|      :|.:|..|.|..:|            ::.|:| |
Human    66 ---NHYSLQRYPGIFNSTTSDAFLQ------SKMRNIFSGRLTAI------------ELFDIL-D 108

  Fly   126 QRVKELYLNKDNH----------FDLVI------SGYFMNDYQLG-----FARKVNAPVVVLAPS 169
            ...|...|...||          |||::      .| |:..:.||     |:..:..|..|.||:
Human   109 HYTKNCDLMVGNHALIQGLKKEKFDLLLVDPNDMCG-FVIAHLLGVKYAVFSTGLWYPAEVGAPA 172

  Fly   170 PPSQM--LNSLIGNPHDKVEKEK--GMTFGQRLDSYISSLLYGIFLRQIDQRNRQYYNEIFGDDP 230
            |.:.:  .|||:.:..:.:::.|  |:....||.  :|.|:...:     :|..|.||
Human   173 PLAYVPEFNSLLTDRMNLLQRMKNTGVYLISRLG--VSFLVLPKY-----ERIMQKYN------- 223

  Fly   231 TMPEYT--DILRNTSLVFFCSHAASEGPIRPSVPAAIEIGGIQIKDKPDPLPKNLEKFLGNAT-H 292
            .:||.:  |::..:||...|:..|.|.| ||::|..:.:|||..| ...|||::|::::..|. |
Human   224 LLPEKSMYDLVHGSSLWMLCTDVALEFP-RPTLPNVVYVGGILTK-PASPLPEDLQRWVNGANEH 286

  Fly   293 GAILLSLGSNVQGSHIKADTVKKIFSVLSNLKQRVIWKWDDLDKTPGKSDNILYSRWLPQDDILA 357
            |.:|:|.|:.|:  ::..|...|:...|..|.|:|||::.. .|.....:|.....||||:|:|.
Human   287 GFVLVSFGAGVK--YLSEDIANKLAGALGRLPQKVIWRFSG-PKPKNLGNNTKLIEWLPQNDLLG 348

  Fly   358 HPSVKLFINHAGKGGISEAQYHGKPMLSLPVFGDQPGNAHAMVKSGFGLTLSLLTLEEEPFRAAV 422
            |..:|.|::|.|...|.|..|||.|::.:|:|||.......:...|.|:.|...|:.|:....|:
Human   349 HSKIKAFLSHGGLNSIFETIYHGVPVVGIPLFGDHYDTMTRVQAKGMGILLEWKTVTEKELYEAL 413

  Fly   423 LEILSNPKYSQRVVKFSSLYRDRPASARESLIFWTEYVIRHHGAAHLQSPLVHMDFIAANNLDI- 486
            :::::||.|.||..|.|.:::|:|.......|:|.:|:|||:||.||::.:..:.|.....|||
Human   414 VKVINNPSYRQRAQKLSEIHKDQPGHPVNRTIYWIDYIIRHNGAHHLRAAVHQISFCQYFLLDIA 478

  Fly   487 -YALIGAISIGLLL------MLKKVVQITCRRLRTKLN 517
             ..|:||..:..||      :.:|:..:..|...:.:|
Human   479 FVLLLGAALLYFLLSWVTKFIYRKIKSLWSRNKHSTVN 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A1	NP_523607.2	GT1_Gtf-like	25..456	CDD:340817	131/468 (28%)
UGT8	NP_001121646.2	Glycosyltransferase_GTB-type	21..502	CDD:415824	149/523 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150686
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.840