Protein Alignment Ugt37A1 and UGT2B7

DIOPT Version :9

• Sequence 1: NP_523607.2
• Gene: Ugt37A1 / 35307
• FlyBaseID: FBgn0026756
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: NP_001065.2
• Gene: UGT2B7 / 7364
• HGNCID: 12554
• Length: 529
• Species: Homo sapiens
• Alignment Length: 507
• Identity: 135/507 - (26%)
• Similarity: 229/507 - (45%)
• Gaps: 84/507 - (16%)

  Fly    37 SHLIISMSVAKILAEQGHNVTVVTVLEPTITHKN------INLVTVPMTKEE----IKQRSETIG 91
            ||.:...::...|.::||.|||:......:...|      |.:....:||.|    |.|:.:...
Human    34 SHWMNIKTILDELIQRGHEVTVLASSASILFDPNNSSALKIEIYPTSLTKTELENFIMQQIKRWS 98

  Fly    92 AKQKNTSSNRFISILNMSGQMDSMLRKMA-DVLKDQR-VKELYLNKDNHFDLVISGYFMNDYQLG 154
            ...|:|....|..:..:......:.||.. ||:.::: :|::   :::.||::.:.......:|
Human    99 DLPKDTFWLYFSQVQEIMSIFGDITRKFCKDVVSNKKFMKKV---QESRFDVIFADAIFPCSEL- 159

  Fly   155 FARKVNAPVVVLAPSPPSQMLNSLIGNPHDKVEKEKG-------------------MTFGQRLDS 200
            .|...|.|.|.           ||..:|....||..|                   |||.:|:.:
Human   160 LAELFNIPFVY-----------SLSFSPGYTFEKHSGGFIFPPSYVPVVMSELTDQMTFMERVKN 213

  Fly   201 YISSLLYGIFLRQIDQRN-RQYYNEIFGDDPTMPEYTD-----ILRNTSLVFFCSHAASEGPIRP 259
            .|..|.:..:....|.:. .|:|:|:.|...|:.|...     ::||:....|      ..|:.|
Human   214 MIYVLYFDFWFEIFDMKKWDQFYSEVLGRPTTLSETMGKADVWLIRNSWNFQF------PYPLLP 272

  Fly   260 SVPAAIEIGGIQIKDKPDPLPKNLEKFL-GNATHGAILLSLGSNVQGSHIKADTVKKIFSVLSNL 323
            :|..   :||:..| ...||||.:|.|: .:..:|.::.||||.|  |::..:....|.|.|:.:
Human   273 NVDF---VGGLHCK-PAKPLPKEMEDFVQSSGENGVVVFSLGSMV--SNMTEERANVIASALAQI 331

  Fly   324 KQRVIWKWDDLDKTPGKSDNI-----LYSRWLPQDDILAHPSVKLFINHAGKGGISEAQYHGKPM 383
            .|:|:|::|.     .|.|.:     || :|:||:|:|.||..:.||.|.|..||.||.|||.||
Human   332 PQKVLWRFDG-----NKPDTLGLNTRLY-KWIPQNDLLGHPKTRAFITHGGANGIYEAIYHGIPM 390

  Fly   384 LSLPVFGDQPGNAHAMVKSGFGLTLSLLTLEEEPFRAAVLEILSNPKYSQRVVKFSSLYRDRPAS 448
            :.:|:|.|||.|...|...|..:.:...|:.......|:..::::|.|.:.|:|.|.:..|:|..
Human   391 VGIPLFADQPDNIAHMKARGAAVRVDFNTMSSTDLLNALKRVINDPSYKENVMKLSRIQHDQPVK 455

  Fly   449 ARESLIFWTEYVIRHHGAAHLQSPLVHMDFIAANNLDIYALIGAISIGLLLM 500
            ..:..:||.|:|:||.||.||:.....:.:...::||:        ||.||:
Human   456 PLDRAVFWIEFVMRHKGAKHLRVAAHDLTWFQYHSLDV--------IGFLLV 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A1	NP_523607.2	GT1_Gtf-like	25..456	CDD:340817	119/461 (26%)
UGT2B7	NP_001065.2	UDPGT	24..525	CDD:278624	135/507 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150465
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.840