Protein Alignment Ugt37A1 and Ugt2a1

DIOPT Version :10

• Sequence 1: NP_523607.2
• Gene: Ugt37A1 / 35307
• FlyBaseID: FBgn0026756
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: XP_063129643.1
• Gene: Ugt2a1 / 63867
• RGDID: 69432
• Length: 737
• Species: Rattus norvegicus
• Alignment Length: 548
• Identity: 138/548 - (25%)
• Similarity: 236/548 - (43%)
• Gaps: 109/548 - (19%)

  Fly    33 SLSPSHLIISMSVAKILAEQGHNVTVVTVLEPTITHKNINLVTVPMTKEEIKQRSETIGAKQKNT 97
            :|..||.:....:.:.|.::.|:|||:..                         |||:..   |:
  Rat   237 ALDGSHWLNIKILLEELVQRNHSVTVLAA-------------------------SETLFI---NS 273

  Fly    98 SSNRFIS-----ILNMSGQMDSMLRKMADVLKDQR---------VKEL--------YLNKDNHFD 140
            |.:.|||     :.....::|.|:..|..:..|.|         .|||        .:||.
  Rat   274 SPDAFISFEEIPVSYTRSKIDEMIEHMIALWLDHRPTPLTMWAFYKELGKLFAAFYKINKQ---- 334

  Fly   141 LVISGYFMNDYQLGFARKVNAPVVVLAPSPPSQMLNSLIG-------------NPHDKVEKEKG- 191
             :..|...|...:...:|....|::   |.|..|...|:.             :|...||:..|
  Rat   335 -ICDGVLKNATLMARLQKGGFDVLI---SDPVTMCGELVALKLGIPFVYTLRFSPAFTVERHCGK 395

  Fly   192 ------------------MTFGQRLDSYISSLLYGIFLRQIDQRNRQYYNEIFGDDPTMPEYTDI 238
                              ||||:|:.:.||..|.....:........||:.:.|...|:.|   .
  Rat   396 IPTPVSYVPAALSELTDQMTFGERVKNTISYSLQDYIFKSYWGEWNSYYSRVLGRPTTLCE---T 457

  Fly   239 LRNTSLVFFCSHAASEGPIRPSVPAAIEIGGIQIKDKPDPLPKNLEKFL-GNATHGAILLSLGSN 302
            :....:....::...|.| ||.:|....:||:..| ...||||.:|:|: .:..||.::.||||.
  Rat   458 MGKAEIWLMRTYWDFEFP-RPYLPNFEFVGGLHCK-PAKPLPKEMEEFVQTSGEHGVVVFSLGSM 520

  Fly   303 VQGSHIKADTVKKIFSVLSNLKQRVIWKWDDLDKTPGK--SDNILYSRWLPQDDILAHPSVKLFI 365
            |:  ::..:....|.|.|:.:.|:|:|::.  .|.|..  |:..|:. |:||:|:|.||..:.||
  Rat   521 VK--NLTEEKANLIASALAQIPQKVLWRYK--GKIPATLGSNTRLFD-WIPQNDLLGHPKTRAFI 580

  Fly   366 NHAGKGGISEAQYHGKPMLSLPVFGDQPGNAHAMVKSGFGLTLSLLTLEEEPFRAAVLEILSNPK 430
            .|.|..||.||.|||.||:.:|:|.|||.|...|...|..:.:::.|:......:||..:::.|.
  Rat   581 THGGTNGIYEAIYHGIPMVGVPMFADQPDNIAHMKAKGAAVEVNMNTMTSADLLSAVRAVINEPF 645

  Fly   431 YSQRVVKFSSLYRDRPASARESLIFWTEYVIRHHGAAHLQSPLVHMDFIAANNLDIYA-LIGAIS 494
            |.:..::.|.::.|:|....:..:||.|:|:||.||.||:.....:.:...::||:.. |:..::
  Rat   646 YKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLSWFQYHSLDVIGFLLACMA 710

  Fly   495 IGLLLMLKKVVQITCRRLRTKLNKVKKQ 522
            ..:||::|     .|..:..|:.|..|:
  Rat   711 SAILLVIK-----CCLFVFQKIGKTGKK 733

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A1	NP_523607.2	GT1_Gtf-like	25..456	CDD:340817	118/479 (25%)
Ugt2a1	XP_063129643.1	None