DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt37A1 and ugt5g1

DIOPT Version :9

Sequence 1:	NP_523607.2	Gene:	Ugt37A1 / 35307	FlyBaseID:	FBgn0026756	Length:	522	Species:	Drosophila melanogaster
Sequence 2:	NP_001107914.1	Gene:	ugt5g1 / 570913	ZFINID:	ZDB-GENE-080305-10	Length:	528	Species:	Danio rerio

Alignment Length:	555	Identity:	167/555 - (30%)
Similarity:	267/555 - (48%)	Gaps:	86/555 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 ALTLL---IYGAQGANILGLFPSLSPSHLIISMSVAKILAEQGHNVTVVTVLEPTITHKN---IN 72
            |||.|   :....|.||| :||. ..||.:....:.:.|...||:.|||...:....|:|   .|
Zfish    10 ALTCLLSVVCCCHGGNIL-VFPE-DGSHWVNMQVILRKLHTHGHSFTVVRSSKSWYIHENSALYN 72

  Fly    73 LVTV-PMTKEEIKQRSETIGAKQKNTSSNRFISILNMS-------GQMD----------SMLRKM 119
            .:|| |:       .:|.:|....|...:|.:::..||       .|.|          .:||.:
Zfish    73 TITVNPV-------ETEDVGQDYFNMLLDRSLALQKMSPLVRFFEQQKDITTVLKVFHNGVLRMV 130

  Fly   120 ADVLKD-QRVKELYLNKDNHFDLVI------SGYFM-NDYQLGF---ARKVNA--PVVVLAPSPP 171
            :.:|.| :.||.|   ::..|||::      :|..: |..||..   .|.:||  ..:..|||||
Zfish   131 SAMLDDAELVKSL---REAKFDLLLTDPAFPAGVLVANFLQLPMVYNVRWLNAGDAHMQTAPSPP 192

  Fly   172 S--QMLNSLIGNPHDKVEKEKGMTFGQRLDS---YISSLLYGIFL-----RQIDQRNRQYYNEIF 226
            |  .|.|||:   ||:      |:|.||:::   |:.|||...::     |::.:|:....:::.
Zfish   193 SYVPMYNSLL---HDQ------MSFLQRVENFLRYLCSLLQERYVIVPIYRELLERHFPPGSDLL 248

  Fly   227 GDDPTMPEYTDI-LRNTSLVFFCSHAASEGPIRPSVPAAIEIGGIQIKDKPDPLPKNLEKFL-GN 289
                :|.:..|| |.....||       :.| ||::|..|.:||.|.| ....||.:||:|: .:
Zfish   249 ----SMQQSADIWLMRMDFVF-------DFP-RPTMPNIIYMGGFQCK-PAQALPVDLEEFMQSS 300

  Fly   290 ATHGAILLSLGSNVQGSHIKADTVKKIFSVLSNLKQRVIWKWDDLDKTPGKSDNILYSRWLPQDD 354
            ..||.:.:|||:.|  ..:.....:.|.|..:.:.|:|:|::.. ::.....:|.|...|.||:|
Zfish   301 GEHGVVFMSLGAMV--GALPRTITEAIASAFAKIPQKVMWRYHG-ERPSTLGNNTLLLEWFPQND 362

  Fly   355 ILAHPSVKLFINHAGKGGISEAQYHGKPMLSLPVFGDQPGNAHAMVKSGFGLTLSLLTLEEEPFR 419
            :|.||..:.|::|.|..||.||.|||.|:|:||:..||..|...:........|.:.||..:.|.
Zfish   363 LLGHPKTRAFVSHGGTNGIYEAIYHGVPVLALPLLFDQFDNVMRLQVRNAARVLQVATLTSQEFL 427

  Fly   420 AAVLEILSNPKYSQRVVKFSSLYRDRPASARESLIFWTEYVIRHHGAAHLQSPLVHMDFIAANNL 484
            ..:.::|.||.|...:.|.|.|:||:|.|..:|..||.|||:||.|||||:|...::.:.:.::|
Zfish   428 EGLKDVLENPLYRSSIRKMSELHRDQPISPLDSATFWIEYVMRHKGAAHLRSEANNLAWYSYHSL 492

  Fly   485 DIYALIGAISIGLLLMLKKVVQITCRRLRTKLNKV 519
            |:...:.||::........|.:..|.|...|..||
Zfish   493 DVLVFLLAIAVIAFWTSVYVCRFLCCRKSIKKRKV 527

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A1	NP_523607.2	GT1_Gtf-like	25..456	CDD:340817	139/476 (29%)
ugt5g1	NP_001107914.1	UDPGT	24..526	CDD:278624	160/538 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170584657
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.840