Protein Alignment Ugt37A1 and ugt2a2

DIOPT Version :10

• Sequence 1: NP_523607.2
• Gene: Ugt37A1 / 35307
• FlyBaseID: FBgn0026756
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: NP_001018306.2
• Gene: ugt2a2 / 553952
• ZFINID: ZDB-GENE-080721-21
• Length: 534
• Species: Danio rerio
• Alignment Length: 543
• Identity: 143/543 - (26%)
• Similarity: 248/543 - (45%)
• Gaps: 58/543 - (10%)

  Fly    13 LALTLLIYGAQGANILGLFPSLSPSHLIISMSVAKILAEQGHNVTV-VTVLEPTITHKNIN---- 72
            |.|..:.......|:| :.|. ..||.....:|...|..:.|.||| |....|||......
Zfish    11 LVLIFIFSFTHAGNVL-VLPG-EYSHWQNMRNVVDELLNRNHTVTVLVCSASPTINFTQQERFQY 73

  Fly    73 -LVTVPMTKEEIKQRS-ETIGAKQKNTSSNRF---ISILNMSGQMDSMLRKMADVL--KDQRVKE 130
             :..||::.:|:...| |.|....::.|.||.   :.|:.:.|::..|.|.|.|.:  .|..:.:
Zfish    74 LVFEVPLSAQELDGASEELIHIWTQHPSPNRLQTALQIIELLGRVRVMHRAMCDSMLRNDALIAQ 138

  Fly   131 LYLNKDNHFDLVISGYFMNDYQLGFARKVNAPVVVLAPSPPSQMLNSLIGN--------PHDKVE 187
            |...|   ||::.:........| .|..:..|:|:.....|...|..:.|.        |..:..
Zfish   139 LSALK---FDVLFNDPMFMCADL-LAEMLGLPLVLSVRISPGFCLERMCGQMPAPPSFVPITQTV 199

  Fly   188 KEKGMTFGQRLDSYISSLLYGIFLR-----QIDQRNRQYYNEIFGDDPTMPEYTDILRNTSLVFF 247
            ....|.|.:|:.:.|:::::.:...     .:|    .||.::.|...||.|   .:....:...
Zfish   200 LTDRMCFMERVQNMIANIVFSVSFYIVAWISLD----SYYTDVLGKPTTMCE---TMGKADIWLI 257

  Fly   248 CSHAASEGPIRPSVPAAIEIGGIQIKDKPDPLPKNLEKFL-GNATHGAILLSLGSNVQGSHIKAD 311
            .::...|.| ||..|....:||:..| ...||.|.:|:|: .:..||.::.||||.::  ::.::
Zfish   258 RTYWDFEYP-RPFPPNFKFVGGLHCK-PAKPLSKEMEEFVQSSGDHGVVVFSLGSMIK--NLTSE 318

  Fly   312 TVKKIFSVLSNLKQRVIWKWDDLDKTPGK-SDNILYSRWLPQDDILAHPSVKLFINHAGKGGISE 375
            ....|.:.|..:.|:|:|::.  .|||.. :.|.....|:||:|:|.||..|.||.|.|..|:.|
Zfish   319 RANTIAAALGQIPQKVVWRYS--GKTPETLAPNTKIYDWIPQNDLLGHPKTKAFITHGGTNGLYE 381

  Fly   376 AQYHGKPMLSLPVFGDQPGNAHAMVKSGFGLTLSLLTLEEEPFRAAVLEILSNPKYSQRVVKFSS 440
            |.|||.||:.||:|.|||.|...|...|..:.|.:.|||.:....|:..:|:||.|.:.:::.|.
Zfish   382 AIYHGVPMVGLPLFADQPDNLLHMKTKGAAVVLDINTLESKDLVDALKTVLNNPSYKESIMRLSR 446

  Fly   441 LYRDRPASARESLIFWTEYVIRHHGAAHLQSPLVHMDFIAANNLDIYALIGAISIGLLL------ 499
            ::.|:|....:..::|.|:|:|:.||.||:.....:.:...:.||:.|.:  :||..|:
Zfish   447 IHHDQPMKPLDQAVYWIEFVMRNKGAKHLRVQAHELSWYQYHCLDVAAFL--LSIAALITFLWVK 509

  Fly   500 ----MLKKVVQITCRRLRTKLNK 518
                :.::.|:.|....:|:.:|
Zfish   510 ACCFLFRRCVRKTRPERKTQKSK 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A1	NP_523607.2	GT1_Gtf-like	25..456	CDD:340817	123/457 (27%)
ugt2a2	NP_001018306.2	UDPGT	23..521	CDD:278624	138/518 (27%)