Protein Alignment Ugt37A1 and UGT2B28

DIOPT Version :9

• Sequence 1: NP_523607.2
• Gene: Ugt37A1 / 35307
• FlyBaseID: FBgn0026756
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: NP_444267.1
• Gene: UGT2B28 / 54490
• HGNCID: 13479
• Length: 529
• Species: Homo sapiens
• Alignment Length: 500
• Identity: 136/500 - (27%)
• Similarity: 228/500 - (45%)
• Gaps: 72/500 - (14%)

  Fly    37 SHLIISMSVAKILAEQGHNVTVVTVLEPTITHKN----INLVTVP--MTKEE----IKQRSETIG 91
            ||.:...::.|.|.::||.|||:......:...|    :.|...|  :||.|    |.|:.:...
Human    34 SHWMNMKTILKELVQRGHEVTVLASSASILFDPNDAFTLKLEVYPTSLTKTEFENIIMQQVKRWS 98

  Fly    92 AKQKNTSSNRFISILNMSGQMDSMLRKMA-DVLKDQRV-KELYLNKDNHFDLVISGYFMNDYQLG 154
            ..||::....|.....:..:...:.|... ||:.:::| |:|   :::.||::.:..|....:|
Human    99 DIQKDSFWLYFSQEQEILWEFHDIFRNFCKDVVSNKKVMKKL---QESRFDIIFADAFFPCGEL- 159

  Fly   155 FARKVNAPVVVLAPSPPSQMLNSLIGNPHDKVEKEKG-------------------MTFGQRLDS 200
            .|..:|.|.|.           ||...|...:|:..|                   |||.:|:.:
Human   160 LAALLNIPFVY-----------SLCFTPGYTIERHSGGLIFPPSYIPVVMSKLSDQMTFMERVKN 213

  Fly   201 YISSLLYGIFLRQIDQRN-RQYYNEIFGDDPTMPE---YTDI-LRNTSLVFFCSHAASEGPIRPS 260
            .|..|.:..:.:..|.:. .|:|:|:.|...|:.|   ..|| |...|..|...|        |.
Human   214 MIYVLYFDFWFQMCDMKKWDQFYSEVLGRPTTLFETMGKADIWLMRNSWSFQFPH--------PF 270

  Fly   261 VPAAIEIGGIQIKDKPDPLPKNLEKFL-GNATHGAILLSLGSNVQGSHIKADTVKKIFSVLSNLK 324
            :|....:||:..| ...||||.:|:|: .:..:|.::.||||.:  |::.|:....|.:.|:.:.
Human   271 LPNIDFVGGLHCK-PAKPLPKEMEEFVQSSGENGVVVFSLGSVI--SNMTAERANVIATALAKIP 332

  Fly   325 QRVIWKWDDLDKTPGKSDNILYSRWLPQDDILAHPSVKLFINHAGKGGISEAQYHGKPMLSLPVF 389
            |:|:|::|. :|......|....:|:||:|:|..|..:.||.|.|..||.||.|||.||:.:|:|
Human   333 QKVLWRFDG-NKPDALGLNTRLYKWIPQNDLLGLPKTRAFITHGGANGIYEAIYHGIPMVGIPLF 396

  Fly   390 GDQPGNAHAMVKSGFGLTLSLLTLEEEPFRAAVLEILSNPKYSQRVVKFSSLYRDRPASARESLI 454
            .|||.|...|...|..:.|...|:.......|:..::::|.|.:.|:|.|.:..|:|.......:
Human   397 WDQPDNIAHMKAKGAAVRLDFHTMSSTDLLNALKTVINDPSYKENVMKLSIIQHDQPVKPLHRAV 461

  Fly   455 FWTEYVIRHHGAAHLQSPLVHMDFIAANNLDIYALIGAISIGLLL 499
            ||.|:|:.|.||.||:.....:.:...::||:        ||.||
Human   462 FWIEFVMCHKGAKHLRVAARDLTWFQYHSLDV--------IGFLL 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A1	NP_523607.2	GT1_Gtf-like	25..456	CDD:340817	121/455 (27%)
UGT2B28	NP_444267.1	UDPGT	24..525	CDD:278624	135/499 (27%)
		egt	<269..506	CDD:223071	77/241 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150534
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.840