Protein Alignment Ugt37A1 and Ugt1a2

DIOPT Version :10

• Sequence 1: NP_523607.2
• Gene: Ugt37A1 / 35307
• FlyBaseID: FBgn0026756
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: NP_958826.1
• Gene: Ugt1a2 / 396527
• RGDID: 1549741
• Length: 533
• Species: Rattus norvegicus
• Alignment Length: 556
• Identity: 157/556 - (28%)
• Similarity: 257/556 - (46%)
• Gaps: 90/556 - (16%)

  Fly    12 VLALTLLIYGAQGANILGLFPSLSPSHLIISMSVAKILAEQGHNVTVVTVLEPTITHKNINLVTV 76
            :|.|...:..|:|..:| :|| :..||.:....|.:.|..:||. .||...|.|:..|..:..|:
  Rat    15 LLLLLCALPWAEGGKVL-VFP-MEGSHWLSMRDVVRELHARGHQ-AVVLAPEVTVHMKGEDFFTL 76

  Fly    77 -----PMTKEEIKQRSETIGAKQKNTSSNRFISILNMSGQMDSMLRKMADVLKDQRVKELYLN-- 134
                 |.||||.::  |.:|..:|......|:.         :....||.:   ::..:||.|
  Rat    77 QTYAFPYTKEEYQR--EILGNAKKGFEPQHFVK---------TFFETMASI---KKFFDLYANSC 127

  Fly   135 -------------KDNHFDLVIS------GYFMNDY----QLGFARKVNAPV---VVLAPSPPSQ 173
                         ..:.||:|::      |..:..|    .:.|.|.|...:   ....|.|.|.
  Rat   128 AALLHNKTLIQQLNSSSFDVVLTDPVFPCGALLAKYLQIPAVFFLRSVPCGIDYEATQCPKPSSY 192

  Fly   174 MLNSL-IGNPHDKVEKEKGMTFGQRLDSYISSLLYGIFLRQIDQRNRQYYNEIFGDDPTMPEYTD 237
            :.|.| :.:.|        |||.||    :.::||.:.|:.|...:...|..:         .::
  Rat   193 IPNLLTMLSDH--------MTFLQR----VKNMLYPLTLKYICHLSITPYESL---------ASE 236

  Fly   238 IL-RNTSLVFFCSHAA---SEGPI-----RPSVPAAIEIGGIQIKDKPDPLPKNLEKFLGNAT-- 291
            :| |..|||...|||:   ..|..     ||.:|..:.||||....| .||.:..|.:: ||:
  Rat   237 LLQREMSLVEVLSHASVWLFRGDFVFDYPRPIMPNMVFIGGINCVIK-KPLSQEFEAYV-NASGE 299

  Fly   292 HGAILLSLGSNVQGSHIKADTVKKIFSVLSNLKQRVIWKWDDLDKTPGKSDNILYSRWLPQDDIL 356
            ||.::.||||.|  |.|......:|...|..:.|.|:|::.. .:....:.|.:..:||||:|:|
  Rat   300 HGIVVFSLGSMV--SEIPEKKAMEIAEALGRIPQTVLWRYTG-TRPSNLAKNTILVKWLPQNDLL 361

  Fly   357 AHPSVKLFINHAGKGGISEAQYHGKPMLSLPVFGDQPGNAHAMVKSGFGLTLSLLTLEEEPFRAA 421
            .||..:.||.|:|..||.|...:|.||:.:|:||||..||..|...|.|:||::|.:..:....|
  Rat   362 GHPKARAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENA 426

  Fly   422 VLEILSNPKYSQRVVKFSSLYRDRPASARESLIFWTEYVIRHHGAAHLQSPLVH-MDFIAANNLD 485
            :..:::|..|.:.:::.|||::|||....:..:||.|||:||.||.||: |..| :.:...::||
  Rat   427 LKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLR-PAAHDLTWYQYHSLD 490

  Fly   486 IYALIGAISIGLLLMLKKVVQITCRRLRTKLNKVKK 521
            :...:.||.:.::.::.|.....||:......:|||
  Rat   491 VIGFLLAIVLTVVFIVYKSCAYGCRKCFGGKGRVKK 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A1	NP_523607.2	GT1_Gtf-like	25..456	CDD:340817	130/475 (27%)
Ugt1a2	NP_958826.1	UDPGT	28..524	CDD:278624	150/539 (28%)