Protein Alignment Ugt37A1 and Ugt1a6b

DIOPT Version :9

• Sequence 1: NP_523607.2
• Gene: Ugt37A1 / 35307
• FlyBaseID: FBgn0026756
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: NP_958812.3
• Gene: Ugt1a6b / 394435
• MGIID: 3580629
• Length: 531
• Species: Mus musculus
• Alignment Length: 547
• Identity: 154/547 - (28%)
• Similarity: 250/547 - (45%)
• Gaps: 94/547 - (17%)

  Fly    25 ANILG---LFPSLSPSHLIISMSVAKILAEQGHNVTV----VTVLEPTITHKNINLVTVPMTKEE 82
            |::||   |......||.:....:.:.|:|:||::.|    |.:|.....:....:.:||.:.||
Mouse    22 ASVLGDKLLVVPQDGSHWLSMKEIVEHLSERGHDIVVLVPEVNLLLGESKYYRRKIFSVPYSLEE 86

  Fly    83 IKQRSETIGAKQKNTSSNRFISILNMSGQM----DSML------RKMADVLKDQRVKELYLNKDN 137
            ::.|..|.|       .|:|:....:.|.:    :|||      .....:|||...  |...::|
Mouse    87 LQTRFRTFG-------RNQFVPGAPLMGPLREYRNSMLTLEMFFSNCQSLLKDSAT--LSFLREN 142

  Fly   138 HFDLVIS------GYFMNDYQLGFARKVNAPVVVL--------------APSPPSQMLNSLIGNP 182
            .||.:.:      |..:.:|       :|.|.|.|              :|||.|.:       |
Mouse   143 KFDALFTDPAMPCGVILAEY-------LNLPSVYLFRGFPCSLEHMLGQSPSPVSYV-------P 193

  Fly   183 HDKVEKEKGMTFGQRLDSYISSLLYGIFLRQIDQRNRQYY----------NEIFGDDPTMPEYTD 237
            ....:....|||.|||.::|.::|          .|..||          .::...|.::|.
Mouse   194 RFYTKFSDHMTFPQRLANFIVNIL----------ENYLYYCLYSKYEIIVTDLLKRDVSLPS--- 245

  Fly   238 ILRNTSLVFFCSHAASEGPIRPSVPAAIEIGGIQIKDKPDPLPKNLEKFLGNAT--HGAILLSLG 300
             |...||.........|.| ||.:|..|.||||..| |...|.:..|.:: ||:  ||.::.|||
Mouse   246 -LHQNSLWLLRYDFVFEYP-RPIMPNMIFIGGINCK-KKGKLTQEFEAYV-NASGEHGIVVFSLG 306

  Fly   301 SNVQGSHIKADTVKKIFSVLSNLKQRVIWKWDDLDKTPGKSDNILYSRWLPQDDILAHPSVKLFI 365
            |.|  |.|......:|...|..:.|.|:|::.. .:....:.|.:..:||||:|:|.||..:.||
Mouse   307 SMV--SEIPEKKAMEIAEALGRIPQTVLWRYTG-TRPSNLAKNTILVKWLPQNDLLGHPKTRAFI 368

  Fly   366 NHAGKGGISEAQYHGKPMLSLPVFGDQPGNAHAMVKSGFGLTLSLLTLEEEPFRAAVLEILSNPK 430
            .|:|..||.|...:|.||:.:|:||||..||..|...|.|:||::|.:..:....|:..:::|..
Mouse   369 THSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKS 433

  Fly   431 YSQRVVKFSSLYRDRPASARESLIFWTEYVIRHHGAAHLQSPLVH-MDFIAANNLDIYALIGAIS 494
            |.:.:::.|||::|||....:..:||.|||:||.||.||: |..| :.:...::||:...:.||.
Mouse   434 YKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLR-PAAHDLTWYQYHSLDVIGFLLAIV 497

  Fly   495 IGLLLMLKKVVQITCRRLRTKLNKVKK 521
            :.::.::.|.....||:......:|||
Mouse   498 LTVVFIVFKCCAYGCRKCFGGKGRVKK 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A1	NP_523607.2	GT1_Gtf-like	25..456	CDD:340817	131/479 (27%)
Ugt1a6b	NP_958812.3	egt	15..503	CDD:223071	148/524 (28%)
		UDPGT	27..522	CDD:278624	148/538 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167840723
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.840