Protein Alignment Ugt37A1 and Ugt1a7c

DIOPT Version :10

• Sequence 1: NP_523607.2
• Gene: Ugt37A1 / 35307
• FlyBaseID: FBgn0026756
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: NP_964004.1
• Gene: Ugt1a7c / 394432
• MGIID: 3032636
• Length: 531
• Species: Mus musculus
• Alignment Length: 535
• Identity: 152/535 - (28%)
• Similarity: 253/535 - (47%)
• Gaps: 57/535 - (10%)

  Fly    17 LLIYGAQGANILGLFPSLSPSHLIISMSVAKILAEQGHNVTVVTVLEPTIT---HKNINLV---- 74
            ||..|...|..|.:.| :..||.....:|.:.|..:||.|.||.   |.::   .|.:|.|
Mouse    17 LLASGLAQAGRLLVVP-MDGSHWFTMQTVVEKLLHKGHEVVVVV---PEVSWQLTKPLNFVVKTY 77

  Fly    75 TVPMTKEEIKQRSET-IGAKQKNTSSNRFISILN--MSGQMDSMLRKMADVLKDQRVKELYLNKD 136
            .|..|:|::.:..:. |.|:.|:......:.:|:  ..|..:.:......:..|:::.| || |.
Mouse    78 AVSHTQEDLNREFKIFIDAQWKSQQEGGILPLLDSPAKGFFELLFSHCRSLFNDKKLVE-YL-KQ 140

  Fly   137 NHFDLVISGYFMNDYQ---LGFARKVNAPVVVLA--------------PSPPSQMLNSLIGNPHD 184
            ..||.|    |::.:.   |..|:..:.|.||.:              |||||.:       |..
Mouse   141 TSFDAV----FLDPFDVCGLTVAKYFSLPSVVFSRGIFCHYLEDAAQCPSPPSYI-------PRM 194

  Fly   185 KVEKEKGMTFGQRLDSYISSLLYGIFLRQIDQRNRQYYNEIFGDDPTMPEYTDILRNTSLVFFCS 249
            .::....|||.:|..:.::.:....|..:..:......:|:.....||   ||:....|:....:
Mouse   195 LLKFTDTMTFKERTRNLLAYMGERAFCHKFFKSAADIASEVLQTPVTM---TDLFSPVSIWLLRT 256

  Fly   250 HAASEGPIRPSVPAAIEIGGIQIKDKPDPLPKNLEKFLGNAT--HGAILLSLGSNVQGSHIKADT 312
            ....|.| ||.:|..|.||||.. .:..||.|..|.:: ||:  ||.::.||||.|  |.|....
Mouse   257 DFVLEFP-RPVMPNVIYIGGINC-HQGKPLSKEFEAYV-NASGEHGIVVFSLGSMV--SEIPEKK 316

  Fly   313 VKKIFSVLSNLKQRVIWKWDDLDKTPGKSDNILYSRWLPQDDILAHPSVKLFINHAGKGGISEAQ 377
            ..:|...|..:.|.|:|::.. .:....:.|.:..:||||:|:|.||..:.||.|:|..||.|..
Mouse   317 AMEIAEALGRIPQTVLWRYTG-TRPSNLAKNTILVKWLPQNDLLGHPKTRAFITHSGSHGIYEGI 380

  Fly   378 YHGKPMLSLPVFGDQPGNAHAMVKSGFGLTLSLLTLEEEPFRAAVLEILSNPKYSQRVVKFSSLY 442
            .:|.||:.:|:||||..||..|...|.|:||::|.:..:....|:..:::|..|.:.:::.|||:
Mouse   381 CNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLH 445

  Fly   443 RDRPASARESLIFWTEYVIRHHGAAHLQSPLVH-MDFIAANNLDIYALIGAISIGLLLMLKKVVQ 506
            :|||....:..:||.|||:||.||.||: |..| :.:...::||:...:.||.:.::.::.|...
Mouse   446 KDRPIEPLDLAVFWVEYVMRHKGAPHLR-PAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVFKCCA 509

  Fly   507 ITCRRLRTKLNKVKK 521
            ..||:......:|||
Mouse   510 YGCRKCFGGKGRVKK 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A1	NP_523607.2	GT1_Gtf-like	25..456	CDD:340817	126/459 (27%)
Ugt1a7c	NP_964004.1	UDPGT	26..522	CDD:278624	145/522 (28%)