Protein Alignment Ugt37A1 and ugt-35

DIOPT Version :10

• Sequence 1: NP_523607.2
• Gene: Ugt37A1 / 35307
• FlyBaseID: FBgn0026756
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: NP_001023694.1
• Gene: ugt-35 / 3565443
• WormBaseID: WBGene00044286
• Length: 536
• Species: Caenorhabditis elegans
• Alignment Length: 564
• Identity: 138/564 - (24%)
• Similarity: 238/564 - (42%)
• Gaps: 92/564 - (16%)

  Fly    10 VIVLALTLLIYGAQGANILGLFPSLSPSHLIISMSVAKILAEQGHNVTVVTVLEPTITHKNINLV 74
            ::...:::|...::..|.|...|..:.||......:|..|:|:|||   ||.|.|.|..|..|..
 Worm     7 ILFFLISILFQNSKSVNFLVYCPLFAHSHHTFLAKIADTLSEEGHN---VTFLAPIIVQKYENFK 68

  Fly    75 TVPMT--------KEEIKQRSETIGAKQKNTSSNRFISILNMSGQMDSMLRKMADVLKDQRVKEL 131
            .:..|        .||:|:..|.:|:...:.......|:.:|...:....:....:.::.|....
 Worm    69 YLKHTTDIIYIQPDEELKKLGEIMGSAGFSKYWTEEPSVFSMIPSIKLFQKMFHKIYENLRADLS 133

  Fly   132 YLN--KDNHFD------LVISGYFMNDYQLGFARKVNAPV------VVLA-----PSPPSQMLNS 177
            .|:  ||..||      |..:...:..| ||.  |...|.      :||:     |:.|:.:.::
 Worm   134 ILDSLKDRKFDAMIYEVLAFNAIAIQQY-LGI--KTLYPTFSVTHGMVLSKSIGEPASPATLSSA 195

  Fly   178 LIGNPHDKVEKEKGMTFGQRLDSYISSLLYGIFLR--QIDQRNRQYYNEIFGDDPTMPEYTDILR 240
            |  :|:.    || |.|.:||.:.:.:.:|.:|::  ::...:..|| ||        :..:...
 Worm   196 L--SPYG----EK-MNFQERLMNTVCAFIYQVFMKPPKMISYSHPYY-EI--------DLKEAES 244

  Fly   241 NTSLVFFCSHAASEGPIRPSVPAAIEIGGIQIKD---KPDPLPKNLEKFLGNATHGAILLSLGSN 302
            ..|.||..|:...:.| ||.:...:.||||.:..   :.:.|.......| |.....:|:|.||.
 Worm   245 KASFVFLNSNPYLDFP-RPMLTKTVLIGGISVNTSQIREERLSDEYHNIL-NIRVKTVLISFGSI 307

  Fly   303 VQGSHIK---ADTVKKIFSVLSNLKQRVIWKW--DDLDKTPGKSDNILYSRWLPQDDILAHPSVK 362
            :..:.:.   ...:.|:.....|:  ..|||:  |:|| ......|:.:.:|:||..:||...:.
 Worm   308 MLSTDMPDRYKSIIVKVIEEFPNV--TFIWKYESDELD-FANNLKNLHFFKWIPQTALLADSRLS 369

  Fly   363 LFINHAGKGGISEAQYHGKPMLSLPVFGDQPGNAHAMVKSGFGLTLSLLTLEE-EPFRAAVLEIL 426
            .||.|||.|.|:|..|.|||.:.:|:|.||..||..:|:....::|....|.. |..|.::.:||
 Worm   370 AFITHAGLGSINELSYMGKPAILVPIFADQLRNAKMLVRHNGSISLEKQDLGNFEKLRVSLAKIL 434

  Fly   427 SNPKYSQRVVKFSSLYRDRPASARESLIFWTEYVIRH--HGAAHLQSPLV-----HMDFIAANNL 484
            .:..:.:.....:....::|.|.||.|       |:|  .||...:.|.:     .|.|.:.|.:
 Worm   435 KDNSFQENAEILARQLNNQPISPRELL-------IKHATFGAEFGELPSLDPYSRQMSFFSLNMI 492

  Fly   485 DIYALIGAISIGL-------------LLMLKKVVQITCRRLRTK 515
            ||:..:|.....|             ||:.||.|:.:....:||
 Worm   493 DIFLFLGVFLAILVYFLFTFLRLLLNLLLKKKAVEKSQENRKTK 536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A1	NP_523607.2	GT1_Gtf-like	25..456	CDD:340817	118/468 (25%)
ugt-35	NP_001023694.1	GT1_Gtf-like	23..448	CDD:340817	113/451 (25%)