Protein Alignment Ugt37A1 and Ugt1a8

DIOPT Version :10

• Sequence 1: NP_523607.2
• Gene: Ugt37A1 / 35307
• FlyBaseID: FBgn0026756
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: NP_787040.2
• Gene: Ugt1a8 / 301595
• RGDID: 708474
• Length: 530
• Species: Rattus norvegicus
• Alignment Length: 540
• Identity: 153/540 - (28%)
• Similarity: 256/540 - (47%)
• Gaps: 57/540 - (10%)

  Fly    13 LALTLLIYGAQGANILG--LFPSLSPSHLIISMSVAKILAEQGHNVTVVTVLEPTIT-H--KNIN 72
            |.|.:.::.|.|....|  |...:..||......:.:.|:.:||.|.||.   |.:: |  |::|
  Rat    10 LPLCVCLFLASGFAQAGRLLVVPMDGSHWFTMQMIVEKLSHRGHEVVVVI---PEVSWHMGKSLN 71

  Fly    73 LV----TVPMTKEEIKQRSETIGAKQKNTSSNRFISILNMSGQ--MDSMLRKMADVLKDQRVKEL 131
            ..    :|..|.|::....:.....|..|......|:|..||:  .:.:......:.||:::.|
  Rat    72 FTVKTYSVSYTLEDLNYHFKFFAHNQWKTQEVGMFSLLKHSGKGFFELLFSHCRSLFKDKKLVE- 135

  Fly   132 YLNKDNHFDLVISGYFMNDYQ---LGFARKVNAPVVVLA--------------PSPPSQMLNSLI 179
            || |.:.||.|    |::.:.   |..|:..:.|.||.:              |||||.:
  Rat   136 YL-KQSSFDAV----FLDPFDVCGLILAKYFSLPSVVFSGGIFCHYLDEGAQCPSPPSYV----- 190

  Fly   180 GNPHDKVEKEKGMTFGQRLDSYISSLLYGIFLRQIDQRNRQYYNEIFGDDPTMPEYTDILRNTSL 244
              |....:....|||.:|:.:::|.:....|.....:...:..:|:.....||   .|:....|:
  Rat   191 --PRILSKFTDTMTFKERVWNHLSYMKERAFCPYFFKTAVEIASEVLQTPVTM---RDLFSPVSI 250

  Fly   245 VFFCSHAASEGPIRPSVPAAIEIGGIQIKDKPDPLPKNLEKFLGNAT--HGAILLSLGSNVQGSH 307
            ..|.:....|.| ||.:|..:.||||.. .:..||.|..|.:: ||:  ||.::.||||.|  |.
  Rat   251 WMFRTDFVLEFP-RPVMPNMVYIGGINC-HQGKPLSKEFEAYV-NASGEHGIVVFSLGSMV--SE 310

  Fly   308 IKADTVKKIFSVLSNLKQRVIWKWDDLDKTPGKSDNILYSRWLPQDDILAHPSVKLFINHAGKGG 372
            |......:|...|..:.|.|:|::.. .:....:.|.:..:||||:|:|.||..:.||.|:|..|
  Rat   311 IPEKKAMEIAEALGRIPQTVLWRYTG-TRPSNLAKNTILVKWLPQNDLLGHPKARAFITHSGSHG 374

  Fly   373 ISEAQYHGKPMLSLPVFGDQPGNAHAMVKSGFGLTLSLLTLEEEPFRAAVLEILSNPKYSQRVVK 437
            |.|...:|.||:.:|:||||..||..|...|.|:||::|.:..:....|:..:::|..|.:.:::
  Rat   375 IYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMR 439

  Fly   438 FSSLYRDRPASARESLIFWTEYVIRHHGAAHLQSPLVH-MDFIAANNLDIYALIGAISIGLLLML 501
            .|||::|||....:..:||.|||:||.||.||: |..| :.:...::||:...:.||.:.::.::
  Rat   440 LSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLR-PAAHDLTWYQYHSLDVIGFLLAIVLTVVFIV 503

  Fly   502 KKVVQITCRRLRTKLNKVKK 521
            .|.....||:......:|||
  Rat   504 YKSCAYGCRKCFGGKGRVKK 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A1	NP_523607.2	GT1_Gtf-like	25..456	CDD:340817	126/460 (27%)
Ugt1a8	NP_787040.2	UDPGT	26..521	CDD:278624	146/520 (28%)