Protein Alignment Ugt37A1 and Ugt2a3

DIOPT Version :10

• Sequence 1: NP_523607.2
• Gene: Ugt37A1 / 35307
• FlyBaseID: FBgn0026756
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: NP_001129341.1
• Gene: Ugt2a3 / 289533
• RGDID: 1308444
• Length: 534
• Species: Rattus norvegicus
• Alignment Length: 538
• Identity: 142/538 - (26%)
• Similarity: 238/538 - (44%)
• Gaps: 91/538 - (16%)

  Fly    37 SHLIISMSVAKILAEQGHNVTVVTVLEPTITHKNINLVTVPMTKEEIKQRSET-IGAKQKNTSSN 100
            ||.:...::.:.||.:||.|||:..  |:|......|  .|:..|.|....|| :.....|...|
  Rat    34 SHWLNLKTILEELAARGHEVTVLKY--PSIIIDQSKL--TPLQFENIPVLYETEVAENHLNEIVN 94

  Fly   101 RFISIL-NMSGQMDSMLRKMADVLKDQRVKELYLNKDNHFDLVISGYFMNDYQLGFARKVNAPVV 164
            ..:::: |:|      |.:.|..|:|     .:|....:|:.:......|...:...|.....|:
  Rat    95 LAVNVIPNLS------LWEAARTLQD-----FFLQLTGNFEDLCRSTLYNQTLMNKLRDAKYDVM 148

  Fly   165 VLAPSPPS----------QMLNSLIGNPHDKVEKEKG-------------------MTFGQRLDS 200
            ||.|..|.          ..:|:|..:....:||..|                   |||.:|:.:
  Rat   149 VLDPVIPCGELVAEVLQIPFVNTLRFSMGYSMEKYCGQLPVPLSYVPVVMGELTDHMTFTERVKN 213

  Fly   201 YISSLLYGIFLRQIDQRN-RQYYNEIFGDDPTMPEYTDILRNTSLVFFCSHAAS----------- 253
            .:.||.:..:|:|.|... .|:|::..|...|               ||.....
  Rat   214 MMLSLFFEFWLQQYDFAFWDQFYSKTLGRPTT---------------FCKTVGKAEIWLIRTYWD 263

  Fly   254 -EGPIRPSVPAAIEIGGIQIKDKPDPLPKNLEKFL-GNATHGAILLSLGSNVQGSHIKADTVKKI 316
             |.| ||.:|....:||:..| ...||||.||:|: .:..||.::.||||.::  ::..:....|
  Rat   264 IEFP-RPYLPNFEFVGGLHCK-PAKPLPKELEEFVQSSGEHGVVVFSLGSMIK--NLTEEKANLI 324

  Fly   317 FSVLSNLKQRVIWKWDDLDKTP---GKSDNILYSRWLPQDDILAHPSVKLFINHAGKGGISEAQY 378
            .|.|:.:.|:|:|::.  .|.|   |.:..||  .|:||:|:|.||..:.||.|.|..||.||.|
  Rat   325 ASALAQIPQKVLWRYS--GKKPATLGPNTRIL--NWIPQNDLLGHPKTRAFITHGGTNGIYEAIY 385

  Fly   379 HGKPMLSLPVFGDQPGNAHAMVKSGFGLTLSLLTLEEEPFRAAVLEILSNPKYSQRVVKFSSLYR 443
            ||.||:.:|:|||||.|...|...|..:.:::.|:......:|:..:::.|.|.:..::.|.::.
  Rat   386 HGVPMVGIPMFGDQPYNIAHMEAKGAAVKVAINTMTSADLLSALRAVINEPSYKENAMRLSRVHH 450

  Fly   444 DRPASARESLIFWTEYVIRHHGAAHLQSPLVHMDFIAANNLDIYALIGAISIGLLLMLKKVVQIT 508
            |:|....:..:||.|:|:||.||.||:.....:.:...::||:...:....:.|..::.|.....
  Rat   451 DQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLSWFQYHSLDVIGFLLVCVVTLTFVITKCSLFM 515

  Fly   509 CRRL-----RTKLNKVKK 521
            ||:.     :.|.|:.||
  Rat   516 CRKCCLRERKKKGNRKKK 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A1	NP_523607.2	GT1_Gtf-like	25..456	CDD:340817	122/466 (26%)
Ugt2a3	NP_001129341.1	UDPGT	25..519	CDD:278624	138/522 (26%)