Protein Alignment Ugt37A1 and Ugt2b15

DIOPT Version :10

• Sequence 1: NP_523607.2
• Gene: Ugt37A1 / 35307
• FlyBaseID: FBgn0026756
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: NP_695226.3
• Gene: Ugt2b15 / 266685
• RGDID: 628623
• Length: 530
• Species: Rattus norvegicus
• Alignment Length: 524
• Identity: 149/524 - (28%)
• Similarity: 245/524 - (46%)
• Gaps: 103/524 - (19%)

  Fly    37 SHLIISMSVAKILAEQGHNVTVVT-----VLEPTITHKNINLVTVP--MTKEEIKQRSETIGAKQ 94
            ||.:...::...|.::||.|||:.     ||:|. ...::...|.|  ::|:|::
  Rat    34 SHWMNIKTILDELVQRGHEVTVLKPSAYYVLDPK-KSPDLKFETFPTSVSKDELE---------- 87

  Fly    95 KNTSSNRFISILNM---SGQMDS------MLRKMADVLKDQRV---KELYLNK-------DNHFD 140
                 |.||.::::   ..|.|:      :|:.|.|...|..:   |:...||       ::.||
  Rat    88 -----NYFIKLVDVWTYELQRDTCLSYSPLLQNMIDGFSDYYLSLCKDTVSNKQLMAKLQESKFD 147

  Fly   141 LVISGYFMNDYQLGFARKVNAPVV----VLAPSPPSQMLNSLIGNPHDKVEKEKG---------- 191
            :::|.                ||.    ::|.......|.||..:|..|:||..|
  Rat   148 VLLSD----------------PVAACGELIAEVLHIPFLYSLRFSPGYKIEKSSGRFILPPSYVP 196

  Fly   192 ---------MTFGQRLDSYISSLLYGIFLRQIDQRN-RQYYNEIFGDDPTMPEYTDILRNTSLVF 246
                     |||..|:.:.|.:|.:..:....:.:. ..:|:||.|...|:.|   .:....:..
  Rat   197 VILSGMGGPMTFIDRVKNMICTLYFDFWFHMFNAKKWDPFYSEILGRPTTLAE---TMGKAEMWL 258

  Fly   247 FCSHAASEGPIRPSVPAAIEIGGIQIKDKPDPLPKNLEKFL-GNATHGAILLSLGSNVQGSHIKA 310
            ..|:...|.| .|::|....|||:|.: .|.||||::|.|: .:..||.::.||||.|  |.:..
  Rat   259 IRSYWDLEFP-HPTLPNVDYIGGLQCR-PPKPLPKDMEDFVQSSGEHGVVVFSLGSMV--SSMTE 319

  Fly   311 DTVKKIFSVLSNLKQRVIWKWDDLDKTPGK-SDNILYSRWLPQDDILAHPSVKLFINHAGKGGIS 374
            :....|...|:.:.|:|:||:|  .|||.. ..|....:||||:|:|.||..|.|:.|.|..|:.
  Rat   320 EKANAIAWALAQIPQKVLWKFD--GKTPATLGPNTRVYKWLPQNDLLGHPKTKAFVTHGGANGVY 382

  Fly   375 EAQYHGKPMLSLPVFGDQPGNAHAMVKSGFGLTLSLLTLEEEPFRAAVLEILSNPKYSQRVVKFS 439
            ||.|||.||:.:|:||:|..|...||..|..:||::.|:.:.....|:.||::||.|.:..|..|
  Rat   383 EAIYHGIPMVGIPMFGEQHDNIAHMVAKGAAVTLNIRTMSKSDLFNALKEIINNPFYKKNAVWLS 447

  Fly   440 SLYRDRPASARESLIFWTEYVIRHHGAAHLQSPLVH-MDFIAANNLDIYALIGAISIGLLLMLKK 503
            :::.|:|....:..:||.|:|:||.||.||: ||.| :.:...::||:        ||.||....
  Rat   448 TIHHDQPMKPLDKAVFWIEFVMRHKGAKHLR-PLGHNLPWYQYHSLDV--------IGFLLTCSA 503

  Fly   504 VVQI 507
            |:.:
  Rat   504 VIAV 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A1	NP_523607.2	GT1_Gtf-like	25..456	CDD:340817	129/470 (27%)
Ugt2b15	NP_695226.3	UDPGT	24..527	CDD:278624	149/524 (28%)