DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt37A1 and ugt-15

DIOPT Version :9

Sequence 1:	NP_523607.2	Gene:	Ugt37A1 / 35307	FlyBaseID:	FBgn0026756	Length:	522	Species:	Drosophila melanogaster
Sequence 2:	NP_506211.1	Gene:	ugt-15 / 183462	WormBaseID:	WBGene00008097	Length:	534	Species:	Caenorhabditis elegans

Alignment Length:	581	Identity:	129/581 - (22%)
Similarity:	227/581 - (39%)	Gaps:	125/581 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 FVIVLALTLLI-----------YGAQGANILGLFPSLSPSHLIISMSVAKILAEQGHNVTVVTVL 62
            |::.|.|..|:           :||..:|.||              .::.||.:.||:   ||:|
Worm     5 FLLTLLLLELVCSYKVLVFNPAFGASHSNFLG--------------KISDILIDAGHD---VTML 52

  Fly    63 EPTITHKNINLVTVPMTKEEIK----QRSETIGAKQKNTSSNR------------FISILN---- 107
            .|.......:||.....|:.|:    .||:.:..:.|.....:            |.|::.
Worm    53 IPVCMESKKDLVGSKKVKKIIRIDQEPRSKLMQEEAKTEEMIKKQIWKLDADITIFFSMIKNFSI 117

  Fly   108 MSGQMDSMLRKMADVLKDQRVKELYLNKDNHFD------LVISGYFMNDYQLGFARKVNAPVVVL 166
            .||.....:.|...:|:..|        :.|||      |.|.|:.:.| .:|....:||..|:.
Worm   118 ASGYQCENIFKQTAILEQLR--------NEHFDLGITESLFICGFPLLD-SIGVKTIINADSVLY 173

  Fly   167 APSPPSQMLNSLIGNPHDKVEKEKGMTFGQRLDSYISSLLYGIFLRQIDQRN-RQYYNEIFGD-- 228
            .     .::...:|.|..                  :|...|::.:.||:.: |:....:||.
Worm   174 L-----DVVKHALGEPAS------------------TSYYPGVYAKNIDRMSFRERVRNLFGMAF 215

  Fly   229 -------------DPTMPEYT------DILRNTSLVFFCSHAASEGPIRPSVPAAIEIGGIQI-- 272
                         :...|.|.      |.:...:..|..|:...:.| .|::|..:.|||:|:
Worm   216 SWYFSWTRFQGELEAIKPYYNKSLTWEDHINGAAYYFINSNQYLDYP-SPTLPKTVFIGGMQVNT 279

  Fly   273 -KDKPDPLPKNLEKFLGNATHGAILLSLGSNVQGSHIKADTVKKIFSVLSNLKQRV-IWKWDDLD 335
             |.....|.|..:..| |.....:|:|.|||.....:..:..:....|.:::.:.. |||::..:
Worm   280 NKHGKVKLEKEWDDLL-NLRKQNVLVSFGSNAFSCDMPDEFKESFLKVFASMPETTFIWKYEQEN 343

  Fly   336 KT-PGKSDNILYSRWLPQDDILAHPSVKLFINHAGKGGISEAQYHGKPMLSLPVFGDQPGNAHAM 399
            .| ..:..|:..:.|:||:||||...:.||:.|.|.|...|..|.|||.:.:|:..|||.||..:
Worm   344 ATLADQLSNVKLTTWMPQNDILADERLTLFVTHGGLGSSMELAYQGKPAVVIPLMADQPRNALML 408

  Fly   400 VKSGFGLTLSLLTL-EEEPFRAAVLEILSNPKYSQRVVKFSSLYRDRPASARESLIFWTEYVIRH 463
            .:.|..|.|....| ..|..|.|:..::.||.|.:...|.:::...:|...::.::...::.::|
Worm   409 TRHGGALQLDKTFLNNSEKIREAIQTVMENPSYKKNAEKLANILSSQPHQPKDVVLKHCDFAVKH 473

  Fly   464 HGAAHLQSPLVHM--------DFIAANNLDIYALIGAISIGLLLMLKKVVQITCRRLRTKL 516
            .....|.|...|:        |...|..|.:..:|..|...::.:.|| |...||..:.|:
Worm   474 GDLKTLNSEGRHLNVFQYYSIDIALAAGLFLVTIISFIIFTIIFVFKK-VYFMCRSDKQKV 533

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A1	NP_523607.2	GT1_Gtf-like	25..456	CDD:340817	108/484 (22%)
ugt-15	NP_506211.1	UDPGT	19..506	CDD:278624	117/537 (22%)
ugt-15	NP_506211.1	Glycosyltransferase_GTB_type	<252..493	CDD:299143	64/242 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.910