Protein Alignment Ugt37A1 and ugt-50

DIOPT Version :10

• Sequence 1: NP_523607.2
• Gene: Ugt37A1 / 35307
• FlyBaseID: FBgn0026756
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: NP_741913.1
• Gene: ugt-50 / 181413
• WormBaseID: WBGene00011564
• Length: 523
• Species: Caenorhabditis elegans
• Alignment Length: 544
• Identity: 130/544 - (23%)
• Similarity: 237/544 - (43%)
• Gaps: 94/544 - (17%)

  Fly    15 LTLLIYGA---QGANILGLFPSLSPSHLIISMSVAKILAEQGHNVTVVTVLEPTITHKNINLVTV 76
            ||.|::|:   ..|.||...||:|.||:::....|.:|...||: ||:.:  |:.:....|....
 Worm    13 LTALLHGSFIVNAAKILVYCPSISKSHVLLCSKYADLLHNAGHD-TVLFI--PSYSKLLDNYDGA 74

  Fly    77 PMTK----EEIKQRSETIGAKQKNTSSNRFISILN-MSGQMDSMLRKMADVLKDQRVKELYLNKD 136
            ...|    ..:.:..:|......|...|..|..:: ::...|..:...||:|  .::.|:....|
 Worm    75 KHAKVWRLHNVTEAYDTKLGTLANVMENSHIGFIDRLTFDADFWIDMCADLL--GKLPEMQHIID 137

  Fly   137 NHFDLVISGYFMNDYQLGFARKVNAPVVVL---------------APSPPSQMLNSLIGNP-HDK 185
            ..|||||... ::.......|..|.|..||               .|:.|| .:.|:..|| ||:
 Worm   138 YKFDLVIYNE-IDPCTPAIVRLFNIPKTVLLSSEAIMDKVAWNLGLPTLPS-YVPSVEENPNHDR 200

  Fly   186 VEKEKGMTFGQRLDS---YISSLLYGIFLRQIDQRNRQYYNEIFGDDPTMPEYTDILRNTSLVFF 247
                  |:|.:|:.:   :..|::.. :|:.|...| .:..|:..|.|::.|   |:||.|||..
 Worm   201 ------MSFFERMSNVYKFFQSIVVH-YLQDIHVLN-LFRKEVSSDFPSIAE---IIRNVSLVLV 254

  Fly   248 CSHAASEGPIRPSVPAAIEIGGIQI-KDKPDPLPKNLEKFLGNATHGAILLSLGS---------N 302
            .:....:.| |......:.:|.::. ||:...|||..:.:......|::.:|.|:         .
 Worm   255 NTDEIFDLP-RSYSSKFVYVGMLEAGKDENVTLPKKQDDYFKKGKSGSVFVSFGTVTPFRSLPER 318

  Fly   303 VQGSHIKA-----------------DTVKKIFSVLSNLKQRVIWKWDDLDKTPGKSDNILYSRWL 350
            :|.|.:.|                 ::..:.||.:.|:        |.:|             |:
 Worm   319 IQLSILNAIQKLPDYHFVVKTTADDESSAQFFSTVQNV--------DLVD-------------WV 362

  Fly   351 PQDDILAHPSVKLFINHAGKGGISEAQYHGKPMLSLPVFGDQPGNAHAMVKSGFGLTLSLLTLEE 415
            ||..:|.|.::|||::|.|...:.|..|:|.||:.:|||.||..|...:.:.|.|..:...|:.:
 Worm   363 PQKAVLRHANLKLFVSHGGMNSVLETMYYGVPMVIMPVFTDQFRNGRNVERRGAGKMVLRETVVK 427

  Fly   416 EPFRAAVLEILSNPKYSQRVVKFSSLYRDRPASARESLIFWTEYVIRHHGAAHLQSPLVHMDFIA 480
            |.|..|:..:|....||..|.:.|.|.:::|.::.|.:..|.::|:::..:.|......::..|.
 Worm   428 ETFFDAIHSVLEEKSYSSSVKRISHLMKNKPFTSEERVTKWIDFVLKYETSEHFDLESNNLSIIE 492

  Fly   481 ANNLDIYALIGAISIGLLLMLKKV 504
            .|:||::..:..||:...::.:|:
 Worm   493 HNHLDLFFYLCIISLLNFVVYRKI 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A1	NP_523607.2	GT1_Gtf-like	25..456	CDD:340817	116/481 (24%)
ugt-50	NP_741913.1	GT1_Gtf-like	26..454	CDD:340817	113/467 (24%)