Protein Alignment Ugt37A1 and ugt-5

DIOPT Version :10

• Sequence 1: NP_523607.2
• Gene: Ugt37A1 / 35307
• FlyBaseID: FBgn0026756
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: NP_506200.1
• Gene: ugt-5 / 179753
• WormBaseID: WBGene00013906
• Length: 534
• Species: Caenorhabditis elegans
• Alignment Length: 585
• Identity: 134/585 - (22%)
• Similarity: 230/585 - (39%)
• Gaps: 133/585 - (22%)

  Fly     8 YFVIVLALTLLIYGAQGANILGLFPSLSPSHLIISMSVAKILAEQGHNVT-----VVTVLEPTIT 67
            :.|.::.:.|.|......|.|.:.|....||:.....:|..||:.||.||     ||.:.:....
 Worm     4 HHVFLIFVLLFIKNVASYNFLVISPVYGFSHMKSMAIIANQLADAGHQVTYFQPFVVELFKDHDL 68

  Fly    68 HKNINLVTVPMTKEEIKQRSETIGAKQKNTSSNRFIS--------------------ILNMSGQM 112
            .||.|:..:....:|         ..:||...:..:|                    ||:.|.|
 Worm    69 IKNPNIEIMNYFHDE---------EGKKNIPGHSVLSDAWTSYKYQSDVGQKIFAPRILHQSFQ- 123

  Fly   113 DSMLRKMADVLKDQRV-KELYLNKDNHFDLVIS------GYFMNDY-------QLGFARKVNAPV 163
             .|.|.|   .:|:.: ::|   ||..||:|:|      |.::.||       .:....::||..
 Worm   124 -EMCRHM---FEDEALHRQL---KDKKFDVVLSETFDFCGLYLADYLEMPAIISVFTGNRLNAIT 181

  Fly   164 VVLA--------PSPPSQMLNSLIGNPHDKVEKEKGMTFGQRLDSY----ISSLLYG-IFLRQID 215
            ..|.        |||.|..              ...|:...|.:::    :||..:| :|.||
 Worm   182 NALGEPSFLHYLPSPSSSF--------------NANMSLYDRFNNFWHKILSSSTFGELFDRQ-- 230

  Fly   216 QRNRQYYNEIFGDDPTMPEYTDILRNTS---------LVFFCSHAASEGP----IRPSVPAAIEI 267
                               |.|:.|.|:         |.....|.::..|    :.|::...|.|
 Worm   231 -------------------YADVYRLTNGKARHWKQILNDVTYHFSNSNPYLDFVIPTIAKVIPI 276

  Fly   268 GG--IQIKDKPDPLPKNLEKFLGNATHGAILLSLGSNVQGSHIKADTVKKIFSVLSNLKQ-RVIW 329
            ||  :..|..| |:.|:|:..| |.....:.:|.|:.:...::..:..:.:.....:.|. ..:|
 Worm   277 GGYTMDYKQVP-PVSKDLDTIL-NLRSSTVFISYGTMISAKYMPDEYKQSMIDFFKDNKNVTFLW 339

  Fly   330 KWDDLDKTPGKS---DNILYSRWLPQDDILAHPSVKLFINHAGKGGISEAQYHGKPMLSLPVFGD 391
            |:::.::...|.   ||:..|.|.||..:||...|||||.|.|.|...|..|..||.:..|:|.|
 Worm   340 KYEEPEEKFIKENIPDNVHLSTWFPQQSLLADKRVKLFITHGGLGSTMELAYSAKPAIVTPLFAD 404

  Fly   392 QPGNAHAMVKSGFGLTLSLLTLEEEPFRAAVLE-ILSNPKYSQRVVKFSSLYRDRPASARESLIF 455
            ||.||..:.:.|....||...:.....::.:|: :|::.||.:...:.:.:..::|.|.||.::.
 Worm   405 QPSNAQMLERHGSVEVLSKHDIPNWKKQSDLLKTMLADKKYQEAATRLADILNNQPISPRELMLK 469

  Fly   456 WTEYVIRHHGAAHLQSPLVHMDFIAANNLDIYALIGAISIGLL-----LMLKKVVQITCRRLRTK 515
            ..|...|......|......|.||...|:|:  :|.::|..|.     :.:..:|:..|:..:.|
 Worm   470 HAENAARFGKIPSLTPFAKDMGFIEFYNIDL--IIYSVSFTLFAIYVTIEIFGIVKNCCKTRKLK 532

  Fly   516  515
             Worm   533  532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A1	NP_523607.2	GT1_Gtf-like	25..456	CDD:340817	117/502 (23%)
ugt-5	NP_506200.1	GT1_Gtf-like	21..456	CDD:340817	113/488 (23%)