Protein Alignment Ugt37A1 and ugt-49

DIOPT Version :10

• Sequence 1: NP_523607.2
• Gene: Ugt37A1 / 35307
• FlyBaseID: FBgn0026756
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: NP_505666.2
• Gene: ugt-49 / 179446
• WormBaseID: WBGene00007070
• Length: 525
• Species: Caenorhabditis elegans
• Alignment Length: 562
• Identity: 151/562 - (26%)
• Similarity: 237/562 - (42%)
• Gaps: 88/562 - (15%)

  Fly     8 YFVIVLALTLLIYGAQGANILGLFPSLSPSHLIISMSVAKILAEQGHNVTV-VTVLEPTITH--- 68
            |..:.|.|:||...|  ..||...||:|.||||.:..:|..|.:.||:|.: :|..|| :|.
 Worm     2 YTFLFLLLSLLAVDA--GKILVYSPSISRSHLISNGRIADALVDAGHDVVMFITEYEP-LTEFTG 63

  Fly    69 -KNINLVTVPMTKEEIKQRSETIGAKQKNTSSNRFISIL----NMSGQMDSMLRKMA-------- 120
             |...::|:.....:..:..:.||....::|...|:..|    ..:|..|.::.:..
 Worm    64 TKKAKVITMKGFSTKFAEDMDGIGEYLLSSSRLSFLERLMFEKTCTGACDDLMTRREELEQLRAY 128

  Fly   121 --DVLKDQRVKEL-------YLNKDNHFDLVISGYFMND---YQLGFARKVNAPVVVLAPSPPSQ 173
              ||...::: :|       ||...||  |.||...:.|   |.||.            |:|.|.
 Worm   129 NFDVAFSEQI-DLCGVGIVRYLGIKNH--LWISTTPIMDAVSYNLGI------------PAPSSY 178

  Fly   174 MLNSLIGNPHDKVEKEKGMTFGQR---LDSYISSLL---YG------IFLRQIDQRNRQYYNEIF 226
            :......:..||      |.|.||   |...|.|:|   ||      :|.:.|
 Worm   179 VPTIEENDNGDK------MDFWQRTFNLYMKIGSILIHRYGTDGTTEVFRKYI------------ 225

  Fly   227 GDDPTMPEYTDILRNTSLVFFCSHAASEGPIRPSVPAAIEIGGIQIKDKPDPLPKNLEKFLGNAT 291
               |..|...:|..|:||.|..|....:.| ||::..||.:||:.|.....||.|.....:....
 Worm   226 ---PDFPNVREIAANSSLCFVNSDEVLDLP-RPTITKAIYVGGLGIPKVSKPLDKKFTNIMSKGK 286

  Fly   292 HGAILLSLGSNVQGSHIKADTVKKIFSVLSNLKQR----VIWKWDDLDKTPGKS-DNILYSRWLP 351
            .|.:::||||.:....:.|...:.:...:..:...    .|.|.|:..|...:. .|:..:.|||
 Worm   287 EGVVIISLGSIIPFGDLPAAAKEGVLRAIQEISDYHFLIKIAKGDNNTKKLVEGIKNVDVAEWLP 351

  Fly   352 QDDILAHPSVKLFINHAGKGGISEAQYHGKPMLSLPVFGDQPGNAHAMVKSGFGLTLSLLTLEEE 416
            |.|||:||.:|||:.|.|..|:.|......|.:.:|||.||..|...:.|.|.|..|..|.:..|
 Worm   352 QVDILSHPRLKLFVMHGGINGLVETAIQAVPTVIVPVFADQFRNGRMVEKRGIGKVLLKLDIGYE 416

  Fly   417 PFRAAVLEILSNPKYSQRVVKFSSLYRDRPASARESLIFWTEYVIRHHGAAHLQSPLVHMDFIAA 481
            .|:..||.:|:.|.|.:..::...:.||:|.|..|.|..||::.|.|.....|......::.|..
 Worm   417 SFKNTVLTVLNTPSYKKNAIRIGKMMRDKPFSPEERLTKWTQFAIDHGVLEELHVEGSRLNTIIY 481

  Fly   482 NNLDIYALIGAISIGLLLMLKKVVQITC--RRLRTKLNKVKK 521
            .|||:.|.:..:.:.:|.:.....:..|  :|.::.:.|.||
 Worm   482 YNLDVIAFVLFVFVAVLHVFIYAFKFLCCKKRSQSNIKKSKK 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A1	NP_523607.2	GT1_Gtf-like	25..456	CDD:340817	129/476 (27%)
ugt-49	NP_505666.2	GT1_Gtf-like	18..443	CDD:340817	123/462 (27%)