Protein Alignment Ugt37A1 and ugt-12

DIOPT Version :10

• Sequence 1: NP_523607.2
• Gene: Ugt37A1 / 35307
• FlyBaseID: FBgn0026756
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: NP_504309.1
• Gene: ugt-12 / 178880
• WormBaseID: WBGene00020592
• Length: 534
• Species: Caenorhabditis elegans
• Alignment Length: 549
• Identity: 145/549 - (26%)
• Similarity: 243/549 - (44%)
• Gaps: 68/549 - (12%)

  Fly    12 VLALTLLIYGAQGANILGLFPSLSPSHLIISMSVAKILAEQGHNVTV-------VTVLEPTITHK 69
            :..||.|.:....:.||...|....||:.....:|.|:|:.||:||:       :..|:..:.:|
 Worm     7 IFLLTFLFFECYSSKILIFNPIFGFSHVKFISKMADIIADHGHHVTLFQPYHIALKNLDGLVKNK 71

  Fly    70 NINLVTVPMTKEEIKQRSETIGAKQKNTS--------SNRFISILNMSGQMDSMLRKMA-DVLKD 125
            ||.::....|..|     |.:.|:.:..|        .|..|....|...:....:|.| :||.|
 Worm    72 NIEILNYHPTHYE-----ELLKAEPQTFSFFWDSYLVGNPVIGAFLMPKLLGGEFKKTAMEVLSD 131

  Fly   126 QR-VKELYLNKDNHFDLVISGYF-MNDYQLGFARKVNAPVVVLAPSPPSQMLNSLIGNPH----- 183
            |: :.||   ||..|||||:..| :..:.|  |..::.|.:.:..:....:.|...|.|.
 Worm   132 QKLINEL---KDRKFDLVIAETFELTGFYL--AHLLDVPCIPMMSAVRYPIFNDQFGQPSLLGHV 191

  Fly   184 ----DKVEKEKGMTFGQRLDSYISSLLYGIFLRQIDQRNRQYYNEIFGDDPTMPEYTDILRNTSL 244
                ..|..|.|  |..||:........||...|:::....:..|..|  ..:|.:.|:::.:.:
 Worm   192 PQIGSAVAGEAG--FYDRLNDMFRFFFMGISQEQLNKYQNYFIEEAIG--RPVPFWKDLVKQSPI 252

  Fly   245 VFFCSHAASEGPIRPSVPAAIEIGGIQIKDKP----DPLPKNLEKFLGNATHGAILLSLGSNVQG 305
            ....|:...:..: ||..|.:::|||.:..|.    ..||:..|..| ......:|:|.||.::.
 Worm   253 YITNSNPYLDYAV-PSTAAIVQVGGITMDLKKLKQVGELPEEYENIL-KERESTVLISFGSVIRS 315

  Fly   306 ----SHIKADTVKKIFSVLSNLKQRVIWKW--DDLDKTPGKSDNILYSRWLPQDDILAHPSVKLF 364
                ...||..: |:|..|.::  ..|||:  |||:.......|:...:|:||..:||...||||
 Worm   316 YEMPESFKAGLI-KVFESLPDV--TFIWKYEKDDLEFQKRLPKNVHLKKWIPQPSLLADKRVKLF 377

  Fly   365 INHAGKGGISEAQYHGKPMLSLPVFGDQPGNAHAMVKSGFGLTLSLLTLEE-EPFRAAVLEILSN 428
            |.|.|.|...|..|.|||.:.:|:||||..||..:.:.|..:......|:. |...|.|.|::|:
 Worm   378 ITHGGLGSTMEVAYTGKPAIVVPIFGDQHHNAVMLARHGGAVAYDKFDLKNGEKLTAVVHEMISS 442

  Fly   429 PKYSQRVVKFSSLYRDRPASARESLIFWTEYVIR--HHGAAHLQSPLVH-MDFIAANNLDI--YA 488
            .||.:.......:..::|...:.:.:...::.|:  :|.|   |.|.:: :.|:|...||:  :.
 Worm   443 TKYQENAEALQHVLFNQPIDPKMNFLNHLDFAIKFPNHRA---QVPAINQLGFVAHYYLDVLLFL 504

  Fly   489 LIGAISIGLLL--MLKKVVQITCRRLRTK 515
            |:.:|.|..|.  :||||:. .|...:||
 Worm   505 LVSSIVITYLAISLLKKVLG-KCLTKKTK 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A1	NP_523607.2	GT1_Gtf-like	25..456	CDD:340817	122/468 (26%)
ugt-12	NP_504309.1	GT1_Gtf-like	21..456	CDD:340817	121/453 (27%)