Protein Alignment Ugt37A1 and ugt-22

DIOPT Version :10

• Sequence 1: NP_523607.2
• Gene: Ugt37A1 / 35307
• FlyBaseID: FBgn0026756
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: NP_502633.1
• Gene: ugt-22 / 178330
• WormBaseID: WBGene00007455
• Length: 534
• Species: Caenorhabditis elegans
• Alignment Length: 560
• Identity: 147/560 - (26%)
• Similarity: 238/560 - (42%)
• Gaps: 84/560 - (15%)

  Fly     2 VGRTKSYFVIVLALTLLIYGAQGANILGLFPSLSPSHLIISMSVAKILAEQGHNVTVVTVLEPTI 66
            ||.|:.|       .:|:|    .|:.|      .||:.:..:|:..|.:.||:   :|||.|.|
 Worm    18 VGLTEPY-------KILMY----TNLFG------HSHIKMLGAVSDTLTDAGHD---LTVLMPVI 62

  Fly    67 THKNINLVTVPMTKEEIKQR-----SETIGAKQK-------NTSSNRFISILN---MSGQMDSML 116
            ..|..|...:..||..||.:     |:||...:|       ..:||....:.:   ||....|..
 Worm    63 DFKQENKTAMKSTKNIIKIQPGQDISKTIETMEKFMTQLWTTDNSNPLFMVFHAPAMSAIFASQC 127

  Fly   117 RKMADVLKDQRVKELYLNKDNHFDLVISGYFMN-DYQLGFARKVNAPVVVLA------------- 167
            ||   ||:|:.:.| .|..:| |||.|:..|.. .|.|..|.|:.|.|.||:
 Worm   128 RK---VLEDKELIE-RLRAEN-FDLAITEPFDTCAYALFEAIKIRAHVAVLSCSRLDHVSKAIGQ 187

  Fly   168 PSPPSQMLNSLIGNPHDKVEKEKGMTFGQRLDSYISSLLYGIFLRQIDQRNRQYYNEIFGDDPTM 232
            |..||.:       |..:....:.||..||..:.:..|:.......|...:.:...||.   |.:
 Worm   188 PIAPSYV-------PGTQSTHGERMTIWQRFMNILHFLMGDFLFSYIGDEDFKVAKEII---PGV 242

  Fly   233 PEYTDILRNTSLVFFCSHAASEGPIRPSVPAAIEIGGIQIK--DKPDPLPKNLEKFLGNATHGAI 295
            ..:.::|...|.: |.:|........|:....|.||||.:|  .|...||:...|.||..... |
 Worm   243 RSWREVLPEASFI-FTNHIPLMDFPAPTFDKIIPIGGISVKTQKKSLELPEKWNKILGLRKKN-I 305

  Fly   296 LLSLGSNVQGSHIKADTVKKIFSVLSNLKQ-RVIWKWD-DLDKTPGKSDNILYSRWLPQDDILAH 358
            |:|.|||.:.:.:.....:.:..|..::.. ..|||:: :.|......||:....||||:::|..
 Worm   306 LVSFGSNARSADMPEHFKQNVLKVAESMPDVTFIWKYENEKDTLADHLDNVYLGDWLPQNELLGD 370

  Fly   359 PSVKLFINHAGKGGISEAQYHGKPMLSLPVFGDQPGNAHAMVKSGFGLTLSLLTL-EEEPFRAAV 422
            |.:.||:.|.|...::|....|||.:.:|:|.||..||:.:.:.|....|....| ..|..|..:
 Worm   371 PRLSLFVTHGGLASVTELALMGKPAVMVPLFADQARNANMLKRHGGAAVLHKTDLGNAETIRNTI 435

  Fly   423 LEILSNPKYSQRVVKFSSLYRDRPASARESLIFWTEYVIRHHGAAHLQSPLVHMDFIAANNLDIY 487
            .::|.|.||.....:.:.:..::|.:.:::||...|:..:......:.....|..:|.      |
 Worm   436 KKVLENEKYRVNAERLAEMLNNQPTNPKDTLIKHVEFAAKFGQLPSMDPYGRHQSYIE------Y 494

  Fly   488 ALIGAISIGLLLMLK------KVVQITCRRLRTKLNKVKK 521
            .|:..|||.|:|:|.      ::::.|. |:.....||||
 Worm   495 YLLDIISIALVLILTTSFISFQLIKCTF-RMCCGSGKVKK 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A1	NP_523607.2	GT1_Gtf-like	25..456	CDD:340817	124/464 (27%)
ugt-22	NP_502633.1	GT1_Gtf-like	24..469	CDD:340817	127/481 (26%)