Protein Alignment Ugt37A1 and Ugt2b37

DIOPT Version :9

• Sequence 1: NP_523607.2
• Gene: Ugt37A1 / 35307
• FlyBaseID: FBgn0026756
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: NP_444445.2
• Gene: Ugt2b37 / 112417
• MGIID: 2148239
• Length: 530
• Species: Mus musculus
• Alignment Length: 536
• Identity: 147/536 - (27%)
• Similarity: 255/536 - (47%)
• Gaps: 89/536 - (16%)

  Fly    37 SHLIISMSVAKILAEQGHNVTVVT-----VLEPTITHKNINLVTVP--MTKEEIKQRSETIGAKQ 94
            ||.:....:...|.::||.|||:.     ||:|. ....:...|.|  :||::::
Mouse    34 SHWMNIKIILDELVQRGHEVTVLRPSAYYVLDPK-KSPGLKFETFPTSVTKDDLE---------- 87

  Fly    95 KNTSSNRFISILNM-------------SGQMDSMLRKMA--------DVLKDQRVKELYLNKDNH 138
                 |.||.:||:             |..|.:|..:::        ||:.::::  :...:::.
Mouse    88 -----NFFIQLLNVWTYELSRDTCLSYSPLMQNMFDELSGYYLSLCKDVVSNRQL--MTKLQESK 145

  Fly   139 FDLVIS------GYFMND-------YQL----GFARKVNAPVVVLAPSPPSQMLNSLIGNPHDKV 186
            ||:::|      |..:.:       |.|    |:..:.::...:|.||....:|:.|.|.
Mouse   146 FDVLLSDPVAFGGELIAELLHIPFLYSLRFTAGYRIEKSSGRFLLPPSYVPVILSGLGGQ----- 205

  Fly   187 EKEKGMTFGQRLDSYISSLLYGIFLRQI--DQRNRQYYNEIFGDDPTMPEYTDILRNTSLVFFCS 249
                 |||.:|:.:.| .:||..|..|:  |::...:|.|..|...|:.|   .:....:....|
Mouse   206 -----MTFIERVKNMI-CMLYFDFWFQMPNDKKWDSFYTEYLGRPTTLAE---TMGQAEMWLIRS 261

  Fly   250 HAASEGPIRPSVPAAIEIGGIQIKDKPDPLPKNLEKFL-GNATHGAILLSLGSNVQGSHIKADTV 313
            :...|.| .|::|....:||:..| ...||||::|::: .:..||.::.||||.|  |:|..:.|
Mouse   262 NWDLEFP-HPTLPNVDYVGGLHCK-PAKPLPKDMEEYVQSSGDHGVVVFSLGSMV--SNITEEKV 322

  Fly   314 KKIFSVLSNLKQRVIWKWDDLDKTPGK-SDNILYSRWLPQDDILAHPSVKLFINHAGKGGISEAQ 377
            ..|...|:.:.|:|:||:|  .|||.. ..|....:||||:|:|.||..|.||.|.|...:.||.
Mouse   323 NAIAWALAQIPQKVLWKFD--GKTPATLGHNTRVYKWLPQNDLLGHPKTKAFITHGGANSVYEAI 385

  Fly   378 YHGKPMLSLPVFGDQPGNAHAMVKSGFGLTLSLLTLEEEPFRAAVLEILSNPKYSQRVVKFSSLY 442
            |||.||:.:|:||:|..|...||..|..:||::.|:.......|:.|::.||.|.:..:..|:::
Mouse   386 YHGIPMIGIPLFGEQHDNIAHMVAKGAAVTLNIRTMSRSDVLNALEEVIENPFYKKNAMWLSTIH 450

  Fly   443 RDRPASARESLIFWTEYVIRHHGAAHLQSPLVH-MDFIAANNLDIYALIGAISIGLLLMLKKVVQ 506
            .|:|....:..:||.|:|:||..|.||: ||.| :.:...::||:...:.|.....:::..|.:.
Mouse   451 HDQPMKPLDRAVFWVEFVMRHKNAKHLR-PLGHNLTWYQYHSLDVIGFLLACVAATVVLTVKCLL 514

  Fly   507 ITCRRLRTKLNKVKKQ 522
            ...|...||..|:|.:
Mouse   515 FIYRFFVTKKKKMKNE 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A1	NP_523607.2	GT1_Gtf-like	25..456	CDD:340817	126/467 (27%)
Ugt2b37	NP_444445.2	UDPGT	24..527	CDD:278624	145/531 (27%)
		Glycosyltransferase_GTB_type	42..>174	CDD:299143	28/149 (19%)
		egt	<270..489	CDD:223071	82/224 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167840538
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.840