DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt37A1 and ugt5f1

DIOPT Version :9

Sequence 1:	NP_523607.2	Gene:	Ugt37A1 / 35307	FlyBaseID:	FBgn0026756	Length:	522	Species:	Drosophila melanogaster
Sequence 2:	XP_017207383.1	Gene:	ugt5f1 / 100415800	ZFINID:	ZDB-GENE-100406-6	Length:	556	Species:	Danio rerio

Alignment Length:	543	Identity:	149/543 - (27%)
Similarity:	272/543 - (50%)	Gaps:	58/543 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 VIVLALTLLIYGAQGANILGLFPSLSPSHLIISMSVAKILAEQGHNVTVVTVLEPTI---THKNI 71
            ::||:|||.::..:   || :||. ..||.:...::.:.|..:||.::|:..|:...   |..:.
Zfish    40 IVVLSLTLPVHCGK---IL-VFPH-EGSHWLNLNTLIEELHHRGHQISVIRALDSWYIPETSPHY 99

  Fly    72 NLVTVPMTKEEIKQ-------RSETIGAKQKNTSSNRFISILNMSGQMDSMLRKMADVL-----K 124
            :.:.||.......|       |...|..:|:.|   ||...:.:..:...|.||:.:::     |
Zfish   100 DSINVPFLLGGDDQFYHSFIFRQLQIRREQRWT---RFKLDMELKEKFSEMHRKICEMVIHIVEK 161

  Fly   125 DQRV-KELYLNKDNHFDLVISGYFMNDYQLGFARKVNAPVV-------------VLAPSPPSQML 175
            :..: |::   |:.:||::::.. .|...:..|..::.|:|             .:||||||.:
Zfish   162 EPAIMKQI---KEANFDIMLTDP-ANGGGVVLAHYLHLPLVFNVQWTVHGEAHFAIAPSPPSYV- 221

  Fly   176 NSLIGNPHDKVEKEKGMTFGQRLDSYI-SSLLYGIFLRQIDQRNRQYYNEIFGDDPTMPEYTDIL 239
                  |....:....|:|.||:.:.: |::...::.|.:........|.:||  |.: :|.::.
Zfish   222 ------PFPLSQLTDSMSFPQRIYNVLFSAVRLFLYRRTVGPHYSALCNRLFG--PGL-DYFELF 277

  Fly   240 RNTSLVFFCSHAASEGPIRPSVPAAIEIGGIQIKDKPDPLPKNLEKFL-GNATHGAILLSLGSNV 303
            :...:....:....:.| ||::|..|.|||... .....|||:||.|| .:..||.|::|||:.|
Zfish   278 QAADIWLMRADFVFDFP-RPTMPNVIYIGGFHC-SPAKALPKDLEDFLQSSGEHGVIVMSLGTLV 340

  Fly   304 QGSHIKADTVKKIFSVLSNLKQRVIWKWDDLDKTPGKSDNILYSRWLPQDDILAHPSVKLFINHA 368
              :.:..|...:|.:..:.|.|:|||::.. |:.....:|.|...||||:|:|.||..::|::|.
Zfish   341 --AQLPMDIADEIVAAFAELPQKVIWRYTG-DRPANVGNNTLLVNWLPQNDLLGHPKTRVFVSHG 402

  Fly   369 GKGGISEAQYHGKPMLSLPVFGDQPGNAHAMVKSGFGLTLSLLTLEEEPFRAAVLEILSNPKYSQ 433
            |..|:.||.|||.|::.||:..||..|...|...|....|.:.|:....|:.|:.|:|::|.|..
Zfish   403 GTNGVFEAIYHGVPIVGLPLVFDQDYNLLKMKHKGVAKVLDIATINRNIFKDALQEVLNDPSYRS 467

  Fly   434 RVVKFSSLYRDRPASARESLIFWTEYVIRHHGAAHLQSPLVHMDFIAANNLDIYALIGAISIGLL 498
            .:.|.|||::|.|....:|.:||||:|:||.|||||::....|.:.:.:::|:...:.::...::
Zfish   468 NMQKLSSLHKDTPLKPLDSALFWTEFVMRHRGAAHLRTDSYKMPWYSYHSVDVGVFLVSVLCFIV 532

  Fly   499 LMLKKVVQITCRRLRTKLNKVKK 521
            .::.|:|:..|.|...|.|:.|:
Zfish   533 FLMFKIVRCLCCRFCAKTNRAKQ 555

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A1	NP_523607.2	GT1_Gtf-like	25..456	CDD:340817	123/461 (27%)
ugt5f1	XP_017207383.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170584589
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.840