Protein Alignment Ugt37A1 and ugt5a4

DIOPT Version :10

• Sequence 1: NP_523607.2
• Gene: Ugt37A1 / 35307
• FlyBaseID: FBgn0026756
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: NP_001170969.3
• Gene: ugt5a4 / 100415798
• ZFINID: ZDB-GENE-100406-1
• Length: 525
• Species: Danio rerio
• Alignment Length: 558
• Identity: 156/558 - (27%)
• Similarity: 254/558 - (45%)
• Gaps: 90/558 - (16%)

  Fly    13 LALTLLIYGAQGANILGLFPSLSPSHLIISMSVAKI-LAEQGHNVTVVTVLEPTITHKNINLVTV 76
            |.|.|.:.....|..|.:.| :..||. |:|.|..: |..:||::|||.........:...|.|
Zfish    10 LFLLLCVLLRSHAGKLLVIP-VDGSHW-INMKVLLVELHSKGHSITVVRASNSWYIEEQSPLYT- 71

  Fly    77 PMTKEEIKQRSETIGAKQKNTSSNRFISILNMSGQMDSMLRKMADVLKDQ---RVKELY------ 132
            .:|.|.        |....:........:|.|..|..|...:||  |.|:   |..|::
Zfish    72 SITVEN--------GEFDADFGEKFLPHLLKMQRQGKSFWTEMA--LADETYSRFTEIHQEICKM 126

  Fly   133 ----------LN--KDNHFDLVISGYFMNDYQLG----FARKVNAPVV-------------VLAP 168
                      :|  ||..:|:|::     |...|    .|.::..|:|             |:||
Zfish   127 TATMFENETLMNSLKDAAYDVVLT-----DPAFGGGVLLAHRLGLPLVYNVRWTMYGEAHFVIAP 186

  Fly   169 SPPSQMLNSLIGNPHDKVEKEKGMTFGQRLDSYISSLLYGIFLRQIDQRNRQY----YNEI---- 225
            ||.|.:       |...::....|||.||:.:.::.::       |..:|.:|    |.|:
Zfish   187 SPLSYV-------PVSGLQLTDKMTFSQRVMNMMTYIM-------ILYKNSKYFDSPYQELTQKY 237

  Fly   226 FGDDPTMPEYTDILRNTSLVFFCSHAASEGPIRPSVPAAIEIGGIQIKDKPDPLPKNLEKFL-GN 289
            ||  |.: .:..:|::..|....:....|.| ||::|..:.:||.|.| ...|||.:||:|: .:
Zfish   238 FG--PNV-NFFSLLQDADLWLMRNDFTFEFP-RPTMPNVVYMGGFQCK-PAKPLPGDLEEFVQSS 297

  Fly   290 ATHGAILLSLGSNVQGSHIKADTVKKIFSVLSNLKQRVIWKWDDLDKTPGKSDNILYSRWLPQDD 354
            ..||.|::|||: |.| .:.::...:|.:..:.|.|:|||::.. .:.....:|.|...|||.:|
Zfish   298 GEHGVIMMSLGA-VFG-QLLSELNDEIAAAFAQLPQKVIWRYTG-PRPANLGNNTLIVNWLPPND 359

  Fly   355 ILAHPSVKLFINHAGKGGISEAQYHGKPMLSLPVFGDQPGNAHAMVKSGFGLTLSLLTLEEEPFR 419
            .|.||..|||:.|.|..|:.||.|||.|::.||:..|||.|...|...|....:...||:...|.
Zfish   360 FLGHPKTKLFVAHGGTNGLQEAIYHGVPIVGLPLAFDQPDNLSRMRAKGTAKIVEFATLDRAVFL 424

  Fly   420 AAVLEILSNPKYSQRVVKFSSLYRDRPASARESLIFWTEYVIRHHGAAHLQSPLVHMDFIAANNL 484
            .|:.|:|.||.|.:.:.:.|.|:.|:|....:..|||.|:|:|:.||.||::....|.:|...::
Zfish   425 EALKEVLHNPSYRENMQRLSKLHHDQPMKPLDRAIFWIEFVMRNKGAPHLRAQSFRMSWIEYQSI 489

  Fly   485 DIYALIGAISIGLLLMLKKVVQITCRRLRTKLNKVKKQ 522
            |:...:..:.:...|:...:.:..|.||..|  |||::
Zfish   490 DVILTLMVMVLVFALVTAYMTKYFCLRLFRK--KVKRE 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A1	NP_523607.2	GT1_Gtf-like	25..456	CDD:340817	133/478 (28%)
ugt5a4	NP_001170969.3	None