Protein Alignment Ugt37A1 and ugt5b3

DIOPT Version :10

• Sequence 1: NP_523607.2
• Gene: Ugt37A1 / 35307
• FlyBaseID: FBgn0026756
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: NP_001348442.2
• Gene: ugt5b3 / 100415792
• ZFINID: ZDB-GENE-100406-5
• Length: 531
• Species: Danio rerio
• Alignment Length: 561
• Identity: 149/561 - (26%)
• Similarity: 264/561 - (47%)
• Gaps: 92/561 - (16%)

  Fly    13 LALTLLIYG---AQGANILGLFPSLSPSHLIISMSVAKILAEQGHNVTVVTVLE--------PTI 66
            :.||||:..   .:..|:| :|| :..||.:....:.:.|..:|||:||:.:.:        |..
Zfish    12 VTLTLLLVTVPVVESGNVL-VFP-VDGSHWVNMNVLVEALHAKGHNITVIRMADSWYIKEFSPHY 74

  Fly    67 THKNINLVTVPMTKEE-----------IKQRSETIGAKQKNTSSNRFISILNMSGQMDSMLRKM- 119
            |  ::||.:.....|:           |.:...|.|..:..      |.:...|.:|..:.|:|
Zfish    75 T--SVNLKSSGGLSEDFIGPFVSRLMNILREGSTWGRVKLE------IEMWQTSLKMIEIEREMI 131

  Fly   120 ADVLKDQRVKELYLNKDNHFDLVIS------GYFMNDYQLGFARKVNAPVV-------------V 165
            .::::||::.:..  |...|||:::      |..:..|       :..|:|             .
Zfish   132 TNMIEDQQLMQSL--KKAKFDLILTDPAMYGGVMLGHY-------LKLPIVYNVRWTIFGEGHFA 187

  Fly   166 LAPSPPSQMLNSLIGNPHDKVEKEKGMTFGQRLDSYISSLLYGIFLRQIDQRNRQYYNEI----F 226
            :||||.|.:       |...:|....|:|.:|:.:.:   :|.|...||.......||.:    .
Zfish   188 IAPSPLSYV-------PVPMLEIPDRMSFLERVKNVV---MYIITETQIAFLIAPTYNALCERFI 242

  Fly   227 GDDPTMPE--YTDILRNTSLVFFCSHAASEGPIRPSVPAAIEIGGIQIKDKPDPLPKNLEKFL-G 288
            |     ||  :.::::...|....:....|.| ||::|..:.:.|.|.|.. .|||::||.|: .
Zfish   243 G-----PEVNFDNLVQEADLWLHRADFVFEYP-RPTMPNIVYMAGFQCKPS-KPLPQDLEDFVQS 300

  Fly   289 NATHGAILLSLGSNVQGSHIKADTVKKIFSVLSNLKQRVIWKWDDLDKTPGK-SDNILYSRWLPQ 352
            :..||.|::|||:.:  ..:..|..:.|....:.|.|::||::.  .|.|.. .:|.|...|:||
Zfish   301 SGNHGVIVMSLGTLI--GQLPDDVAEAIAEAFAELPQKIIWRYK--GKRPSALGNNTLVMDWMPQ 361

  Fly   353 DDILAHPSVKLFINHAGKGGISEAQYHGKPMLSLPVFGDQPGNAHAMVKSGFGLTLSLLTLEEEP 417
            :|:|.||..:.|:.|.|..|:.||.|||.|::...:..|||.|...|...|....:...|:::|.
Zfish   362 NDLLGHPKTRAFVAHGGTNGVQEAIYHGVPIIGFGLIFDQPDNLSKMRVRGAAKNVDFATMDKES 426

  Fly   418 FRAAVLEILSNPKYSQRVVKFSSLYRDRPASARESLIFWTEYVIRHHGAAHLQSPLVHMDFIAAN 482
            |...|.|:|.:|.|.:.:.:.|.|::|.|....::.|||.|:|:||.|||||::....|.:.:.:
Zfish   427 FLTTVKEVLYDPSYRENMQRLSRLHKDVPVKPLDNAIFWIEFVMRHKGAAHLRTESYKMPWYSYH 491

  Fly   483 NLD-IYALIGAISIGLLLMLKKVVQITCRRLRTKLNKVKKQ 522
            ::| |..||.|:|: ::|.:..|::..|.|:..:..|.|::
Zfish   492 SVDVILVLISAVSL-IILSIYAVIRYFCCRICMRTTKNKRE 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A1	NP_523607.2	GT1_Gtf-like	25..456	CDD:340817	121/477 (25%)
ugt5b3	NP_001348442.2	None