Protein Alignment Ugt37A1 and ugt1a4

DIOPT Version :10

• Sequence 1: NP_523607.2
• Gene: Ugt37A1 / 35307
• FlyBaseID: FBgn0026756
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: NP_001170815.3
• Gene: ugt1a4 / 100384901
• ZFINID: ZDB-GENE-080227-3
• Length: 520
• Species: Danio rerio
• Alignment Length: 552
• Identity: 158/552 - (28%)
• Similarity: 263/552 - (47%)
• Gaps: 80/552 - (14%)

  Fly    13 LALTLLIYGAQGANILGLFPSLSPSHLIISMSVAKILAEQGHNVTVVTVLEPTIT---HKNINLV 74
            |.:.|.::|:..|..|.:.|| ..||.:....|.:.|..:|:.| ||.:.|.:::   .:....:
Zfish     6 LLVGLFLFGSAEAGKLLVIPS-DGSHWLGMKPVVEELGRRGNQV-VVVIPEASLSMGPSEKTTTL 68

  Fly    75 TVPM--TKEEIK-----QRSETIGAKQKNTSSNRFISILNMSGQMDSMLRKMADVL-KDQRVKEL 131
            |.|:  ||.|:.     ..:|.:........|..|:..|.:....:.::|....:| .:..:|:|
Zfish    69 TYPVNYTKAELHMVLEGNLTEILSTDFSTELSKFFVFFLQLKVLQNFIVRNAEGLLFNEDLMKKL 133

  Fly   132 YLNKDNHFDLVIS------GYFMNDYQL--GFARKVNAPVVV--LA---PSPPSQMLNSLIGNPH 183
               :|..||.:::      |...::|..  ....:||.|..|  ||   |||||.:       |.
Zfish   134 ---QDCKFDAILTDPFEPVGVIASEYLSIPAIYMQVNLPCGVDSLASQCPSPPSYV-------PQ 188

  Fly   184 DKVEKEKGMTFGQRLDSYISSLLYGIFLR-------QIDQRNRQYYNEIFGDDPTMPEYTDILRN 241
            ........|...||..:.:.:||..:..|       :|..|..|....|          .:|:..
Zfish   189 RNTHFTDQMNIWQRCINLVRTLLQHMACRYMYAEADEIASRFLQRRASI----------VEIMNR 243

  Fly   242 TSLVFFCSHAASEGPIRPSVPAAIEIGGIQIKDKPDPLPKNLEKFL-GNATHGAILLSLGSNVQG 305
            .:|.......|.|.| ||.:|..:.|||:..| ||.||.|.||:|: |:..||.::.:|||.|
Zfish   244 ATLWLMRFDFAFEFP-RPLMPNMVMIGGMATK-KPKPLSKELEEFVNGSGEHGFVVFTLGSMV-- 304

  Fly   306 SHIKADTVKKIFSVLSNLKQRVIWKWDD--LDKTPGKSDNILYSRWLPQDDILAHPSVKLFINHA 368
            |.:.....::.|.....:.|||:|::..  .:..|   .|:...:||||:|:|.||.|:.|:.|.
Zfish   305 SQLPEAKAREFFEAFRQIPQRVLWRYTGPVPENAP---KNVKLMKWLPQNDLLGHPKVRAFVTHG 366

  Fly   369 GKGGISEAQYHGKPMLSLPVFGDQPGNAHAMVKSGFGLTLSLLTLEEEPFRAAVLEILSNPKYSQ 433
            |..||.|...:|.||:.||:||||..||..:|..|...:|::..:..|....|:.:::::..|.:
Zfish   367 GSHGIYEGICNGVPMVMLPLFGDQGDNAQRLVSRGVAESLTIYDVTSEKLLVALKKVINDKSYKE 431

  Fly   434 RVVKFSSLYRDRPASARESLIFWTEYVIRHHGAAHLQSPLVH-MDFIAANNLDIYALIGAISIG- 496
            :::|.|:::||||....:..:||||:|:||.||.||: |..| :::|..::||:        ||
Zfish   432 KMMKLSAIHRDRPIEPLDLAVFWTEFVMRHKGAEHLR-PAAHDLNWIQYHSLDV--------IGF 487

  Fly   497 LLLMLKKVVQIT------CRRLRTKLNKVKKQ 522
            |||:|..|:.:|      |.|...|.::.||:
Zfish   488 LLLILLTVIFVTVKSCMFCFRKCFKKSQKKKK 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A1	NP_523607.2	GT1_Gtf-like	25..456	CDD:340817	126/464 (27%)
ugt1a4	NP_001170815.3	None