Protein Alignment Ugt37A1 and ugt2b3

DIOPT Version :10

• Sequence 1: NP_523607.2
• Gene: Ugt37A1 / 35307
• FlyBaseID: FBgn0026756
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: NP_001170812.2
• Gene: ugt2b3 / 100384898
• ZFINID: ZDB-GENE-100402-2
• Length: 527
• Species: Danio rerio
• Alignment Length: 574
• Identity: 143/574 - (24%)
• Similarity: 251/574 - (43%)
• Gaps: 117/574 - (20%)

  Fly    10 VIVLALTLLIYGAQGANIL-----GLFPSLSPSHLIISMSVAKILAEQGHNVTVVTVLEP----- 64
            |..|:|..:....|..|||     |       ||.|....|...|.::|||   ||||.|
Zfish     5 VCFLSLLTVFSAGQCGNILVWHTEG-------SHWINLKIVLDTLLDRGHN---VTVLMPDGALF 59

  Fly    65 -------TITHKNINLVTVPMTKE--------------------EIKQRSETIGAKQKNTSSNRF 102
                   ..:::|.::.|.....:                    :|:.:...:|::.::...:..
Zfish    60 MKAKESDRFSYQNFSVSTSAQDMQDFLDELLHFSVFEMEQLNLLQIQMKFFDLGSRHQDMGLSYC 124

  Fly   103 ISILNMSGQMDSMLRKMADVLKDQRVKELYLNKDNHFDLVISG--YFMNDYQLGFARKVNAPVVV 165
            ..||.....||.:                   |...||:::|.  |..:|.   .|..:|.|:|.
Zfish   125 DGILKSPELMDKL-------------------KTGKFDVLLSDPMYPCSDI---VAEVLNVPLVF 167

  Fly   166 L---------------APSPPSQMLNSLIGNPHDKVEKEKGMTFGQRLDS---YISSLLYGIFL- 211
            .               .|:|||.:..:: ....||      |:|.:|:.:   |:|...:.|..
Zfish   168 TLRFSIAHTMERICGQIPAPPSYVPGAM-SKLTDK------MSFTERIFNTLFYLSMDTFSIIAW 225

  Fly   212 RQIDQRNRQYYNEIFGDDPTMPEYTDILRNTSLVFFCSHAASEGPIRPSVPAAIEIGGIQIKDKP 276
            ::.|    .||.|.|| .||  .|.:::....:....::...|.| ||.||....|||:.. ...
Zfish   226 KKFD----NYYTEYFG-RPT--SYCEMMGRADIWLIRTYWDFEFP-RPFVPNFKYIGGLHC-TPA 281

  Fly   277 DPLPKNLEKFL-GNATHGAILLSLGSNVQGSHIKADTVKKIFSVLSNLKQRVIWKWDDLDKTPGK 340
            .||||::|:|: .:...|.::.:|||.:  ..:..:...:|.|.|:.:.|:|:|::.. :|....
Zfish   282 KPLPKDMEEFVQSSGDDGIVVFTLGSMI--DKVPKEMSNRIASALAQIPQKVLWRYGG-EKPDTL 343

  Fly   341 SDNILYSRWLPQDDILAHPSVKLFINHAGKGGISEAQYHGKPMLSLPVFGDQPGNAHAMVKSGFG 405
            .:|....:|:||:|:|.||..:.||.|.|..||.||.|||.||:.:|:|||||.|...|...|..
Zfish   344 GENTRIYKWMPQNDLLGHPKTRAFITHGGTNGIYEAIYHGVPMVGIPLFGDQPDNMVHMTTRGAA 408

  Fly   406 LTL-SLLTLEEEPFRAAVLEILSNPKYSQRVVKFSSLYRDRPASARESLIFWTEYVIRHHGAAHL 469
            :.: |:.:::.:.....:..::::|.|.:..::.|.::.|||....:..:||.|:|:|:.||.||
Zfish   409 VVVDSIKSMQPQELVDKLNTVINDPSYKENAMRLSRIHHDRPMKPLDESVFWIEFVMRNKGAKHL 473

  Fly   470 QSPLVHMDFIAANNLDIYALIGAISIGLLL-----MLKKVVQITCRRLRTKLNK 518
            :....::.:...:.||::|.:..: :.|:|     |.|..:...|.|.:.|..|
Zfish   474 RVEAHNLTWYQYHCLDVFAFLTTV-LTLVLYICFKMAKFFIMRCCFRSKRKSKK 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A1	NP_523607.2	GT1_Gtf-like	25..456	CDD:340817	119/490 (24%)
ugt2b3	NP_001170812.2	UDPGT	20..523	CDD:278624	137/554 (25%)