DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment La and SLF1

DIOPT Version :9

Sequence 1:	NP_477014.1	Gene:	La / 35305	FlyBaseID:	FBgn0011638	Length:	390	Species:	Drosophila melanogaster
Sequence 2:	NP_010803.3	Gene:	SLF1 / 852127	SGDID:	S000002923	Length:	447	Species:	Saccharomyces cerevisiae

Alignment Length:	201	Identity:	45/201 - (22%)
Similarity:	89/201 - (44%)	Gaps:	51/201 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 KQERAIIRQVEYYFGDANLNRDKFLREQIGKNEDGWVPLSVLVTFKRLASLST--DLSEIVAALN 111
            |...:|..|:|:||.:.||..|:|||.:..|..||::|:|::..|.|:.:||.  |.:.|:|::
Yeast   270 KSIESIKNQIEFYFSEENLKTDEFLRSKFKKANDGFIPMSLIGKFYRMVNLSLGGDPNLILASM- 333

  Fly   112 KSEEGLVEISEDKLSLRRHPERPIPEHNEERRKEIQ------ERTAYAKGF-PLDSQISELLDFA 169
                                 |.:.:|.|....||.      .:...|..| ||::......::|
Yeast   334 ---------------------REVLQHKETNHLEIALGSIEGAQKNMADDFNPLENYFIRRENWA 377

  Fly   170 -----ANYDKVVNLTMRKHYDK-----PTKSYKFKG--SIFLTFETKDQAKAFLEQEKIVYKERE 222
                 :|:|:..:.|.:.:.:|     ...:|.:.|  :.|.:.|...::::        |.:.|
Yeast   378 EYAMESNFDENDDETEKYNIEKLLGPNDLDNYSYMGYPNFFPSNENGKKSQS--------YDQGE 434

  Fly   223 LLRKWQ 228
            :.|:::
Yeast   435 ISRQFE 440

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
La	NP_477014.1	LARP_3	47..129	CDD:153397	24/81 (30%)
		RRM1_La	150..226	CDD:240737	15/88 (17%)
		RRM_SF	263..338	CDD:302621
SLF1	NP_010803.3	LHP1	3..443	CDD:227520	45/201 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	48	1.000	Domainoid score	I2987
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22792
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.100