DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment La and LARP1a

DIOPT Version :9

Sequence 1:	NP_477014.1	Gene:	La / 35305	FlyBaseID:	FBgn0011638	Length:	390	Species:	Drosophila melanogaster
Sequence 2:	NP_001190354.1	Gene:	LARP1a / 832242	AraportID:	AT5G21160	Length:	833	Species:	Arabidopsis thaliana

Alignment Length:	357	Identity:	65/357 - (18%)
Similarity:	139/357 - (38%)	Gaps:	94/357 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 IIRQVEYYFGDANLNRDKFLREQIGKNEDGWVPLSVLVTFKRLASLSTDLSEIVAALNKSEEGLV 118
            :::||||||.|.||..|.:|...:  :|:||||..::..|||:.:::.|:..||.||..|..  |
plant   282 VLKQVEYYFSDENLENDHYLISLM--DEEGWVPTKIIAGFKRVKAMTMDVDFIVYALGFSNS--V 342

  Fly   119 EISEDKLSLRRHPERPIPEHNEERRKEIQERTAYAKGFPLDSQISELLDFA-ANYDKVVNLTMRK 182
            |:..|                     :|::|..::...|...:.:...... .:.|...::|...
plant   343 EVQGD---------------------QIRKRDKWSDWIPASKKSTSAETIGDGDKDSPKSITSGD 386

  Fly   183 HYDKPTK---------------------SYKFKGSIFLTFETKDQAKAFLEQEKIVYKERELLRK 226
            ::..|:|                     :|| .|::          |:..::::.|   .:|...
plant   387 NFGNPSKGSSKPTVSDFSSEGAQSSRTNNYK-SGNL----------KSSADEKRNV---EDLSND 437

  Fly   227 WQVDYLKEKQEEYAQKNEKRKNKKEAKPEPAFELPKNAIVVFEGAPETSSREEIREAFEKIKDFE 291
            :...:|.:::.:...::.::.....:|.           :.:|........::|:         :
plant   438 FSNTFLLDEELDLEHRSPRKSGLSMSKS-----------IEYEDDDMAVDDQDIQ---------K 482

  Fly   292 VAYIEFAKGETKGS-VRLTEADAAEKYIAK-VEEGKLKFKDEVSLSLRKATEEEEKEFIDKAIEF 354
            :..:....|::.|: :..|||....|.:|. :.:|...|:.|  |..:::...:....:|
plant   483 LVIVTQNSGKSDGAGIGGTEAKNIPKELASTINDGLYYFEQE--LKKKRSGRRKNNSHLD----- 540

  Fly   355 MKKRRDFTRNKGKRFNRKRHGGNDHKHGGGKK 386
               .:|.....|:..|.|. |.|...:.||::
plant   541 ---TKDGKIKSGEGLNTKL-GENSAANDGGEE 568

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
La	NP_477014.1	LARP_3	47..129	CDD:153397	28/74 (38%)
		RRM1_La	150..226	CDD:240737	11/97 (11%)
		RRM_SF	263..338	CDD:302621	13/76 (17%)
LARP1a	NP_001190354.1	LAM	279..351	CDD:153396	29/93 (31%)
		DM15	670..710	CDD:128927
		DM15	712..749	CDD:128927
		DM15	750..785	CDD:128927
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000