DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment La and La1

DIOPT Version :9

Sequence 1:	NP_477014.1	Gene:	La / 35305	FlyBaseID:	FBgn0011638	Length:	390	Species:	Drosophila melanogaster
Sequence 2:	NP_567904.1	Gene:	La1 / 829408	AraportID:	AT4G32720	Length:	433	Species:	Arabidopsis thaliana

Alignment Length:	443	Identity:	108/443 - (24%)
Similarity:	182/443 - (41%)	Gaps:	124/443 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 EEAAGGFTKQERAIIRQVEYYFGDANLNRDKFLREQIGKNEDGWVPLSVLVTFKRLA-------- 97
            ||.|       :.::||||:||.|:||..|.||::.:.::|||.|.|:::.:|.::.
plant     8 EETA-------KTVLRQVEFYFSDSNLPIDDFLKKTVTESEDGLVSLALICSFSKMRGYLKLGDS 65

  Fly    98 ---SLSTDLSEIVAALNKSEEGLVEISEDKLSLRRHPERPIPEHNEERRKEIQERTAYAKGFPLD 159
               .:..|..:.||...::...| :||:|...:.|..|.   ...|:..:::..||..|..|..|
plant    66 KGDDIPEDTIKAVADTLRTSSAL-KISDDGKKVGRSTEL---LKLEDLIEQLNARTVAASPFSYD 126

  Fly   160 SQISELLDFAANYDKVVNLTMRKHYDKPTKSYKFKGSIFLTFETKDQAKAFLEQEKIVY--KERE 222
            .:..::..|.:.|.||.::.|.:|.   .:|..|.|...:.|.|::.|:..::| .:|:  :|.|
plant   127 VKREDVESFFSQYGKVNSVRMPRHV---AESRIFSGVALVEFPTEEDAQNVMKQ-NLVFAGQELE 187

  Fly   223 LLRKWQVDYLKEKQE-EYA----QK-NEKRKNKKEAKPEPAFE--LPKNAIVVF-------EGAP 272
            |..|.:.|..:||.| ::|    || :..:||..:.|...|:|  .||..|:.|       ||..
plant   188 LKPKKEFDNEREKDEVKFANYQPQKGSANQKNGSDHKNNSAYEPDYPKGLIISFTLKRSAEEGTT 252

  Fly   273 ETSS-----------------------------------------------------------RE 278
            |..|                                                           ||
plant   253 EQKSSEEPTDKTMEESETKPADTPDADKENTGEVQAEGAEDEDDEKEEKGALATHKDNKDVVLRE 317

  Fly   279 EIREAFEKIKDFEVAYIEFAKGETKGSVRLTEADAAEKYIAK---VEEGKLKFKDEVSLSLRKAT 340
            :::..|.|..|  |.:::|..|...|.:|..|.:|::|..|.   ..||.|..|:.::: |....
plant   318 DLKAVFGKFGD--VKFVDFKMGSETGYLRFDEPEASQKARAAAVLANEGGLAVKNFIAV-LEPVI 379

  Fly   341 EEEEKEFIDKAIEFMKKRRDFTRNKGK-RFNRKRHGGNDHKHGG--GKKARGD 390
            .|.|||:             :|..:.| ||::...||...:.||  |:|...|
plant   380 GEAEKEY-------------WTLLRSKDRFDKGGRGGRGGRRGGRFGRKRGSD 419

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
La	NP_477014.1	LARP_3	47..129	CDD:153397	25/92 (27%)
		RRM1_La	150..226	CDD:240737	21/77 (27%)
		RRM_SF	263..338	CDD:302621	25/143 (17%)
La1	NP_567904.1	LA_like_plant	10..99	CDD:153399	26/96 (27%)
		RRM1_La	117..189	CDD:409733	20/75 (27%)
		RRM_SF	316..388	CDD:418427	23/87 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	82	1.000	Inparanoid score	I2356
OMA	1	1.010	-	-		QHG54025
OrthoDB	1	1.010	-	-		D882725at2759
OrthoFinder	1	1.000	-	-		FOG0002882
OrthoInspector	1	1.000	-	-		oto3042
orthoMCL	1	0.900	-	-		OOG6_102594
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.880