Protein Alignment La and Ssb

DIOPT Version :9

• Sequence 1: NP_477014.1
• Gene: La / 35305
• FlyBaseID: FBgn0011638
• Length: 390
• Species: Drosophila melanogaster
• Sequence 2: NP_001103615.1
• Gene: Ssb / 20823
• MGIID: 98423
• Length: 415
• Species: Mus musculus
• Alignment Length: 390
• Identity: 128/390 - (32%)
• Similarity: 199/390 - (51%)
• Gaps: 48/390 - (12%)

  Fly    27 AKNGDAKKDPAPAAEEAAGGFTKQERAIIRQVEYYFGDANLNRDKFLREQIGKNEDGWVPLSVLV 91
            |:|||.:|            .|..|..|..|:||||||.||.|||||:||| |.::|||||..::
Mouse     2 AENGDNEK------------MTALEAKICHQIEYYFGDFNLPRDKFLKEQI-KLDEGWVPLETMI 53

  Fly    92 TFKRLASLSTDLSEIVAALNKSEEGLVEISEDKLSLRRHPERPIPEHNEERRKEIQERTAYAKGF 156
            .|.||..|:||.:.||.||:||:..|:|:|.||..:||.|.||:||..:|.:.:::.|:.|.|||
Mouse    54 KFNRLNRLTTDFNVIVQALSKSKAKLMEVSADKTKIRRSPSRPLPEVTDEYKNDVKNRSVYIKGF 118

  Fly   157 PLDSQISELLDFAANYDKVVNLTMRKHYDKPTKSYKFKGSIFLTFETKDQAKAFLEQEKIVYKER 221
            |.|:.:.::.::..:..:::|:.||:...|     .||||||..|::...||.|:|.....||:.
Mouse   119 PTDATLDDIKEWLDDKGQILNIQMRRTLHK-----TFKGSIFAVFDSIQSAKKFVEIPGQKYKDT 178

  Fly   222 ELLRKWQVDYLKEKQEEYAQKNE----KRKNKKEAKPEP------AFELPKNAIVVFEG-APETS 275
            .||..::.||..:|.||..|...    |.|.:.|.:.:|      |.|.....::.|.| ..:.:
Mouse   179 NLLILFKEDYFAKKNEERKQSKVEAKLKAKQEHEGRHKPGSTETRALEGKMGCLLKFSGDLDDQT 243

  Fly   276 SREEIREAFEKIKDFEVAYIEFAKGETKGSVRLTE--ADAAEKYIAKVEEGKLKFKD-EVSLSLR 337
            .||::...|.  ...|:.:::||:|..:|.:...|  .:|.|| ......|.|..:: :|:..:.
Mouse   244 CREDLHFLFS--NHGEIKWVDFARGAKEGIILFKEKAKEALEK-ARNANNGNLLLRNKKVTWKVL 305

  Fly   338 KATEEEE--KEFIDKAIEFMKKRRDFTRNKGKRFN--------RKRHG---GNDHKHGGGKKARG 389
            :...|:|  |:..|...|.:.|.:....:.|.||.        |:..|   ||...:.|..|.||
Mouse   306 EGHAEKEALKKITDDQQESLNKWKSKGGHAGGRFKGSHVFTAARRFKGKGKGNRPGYAGAPKGRG 370

  Fly   390  389
            Mouse   371  370

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
La	NP_477014.1	LARP_3	47..129	CDD:153397	43/81 (53%)
		RRM1_La	150..226	CDD:240737	25/75 (33%)
		RRM_SF	263..338	CDD:302621	17/78 (22%)
Ssb	NP_001103615.1	LARP_3	10..91	CDD:153397	43/81 (53%)
		RRM1_La	112..183	CDD:240737	25/75 (33%)
		RRM_3	230..333	CDD:285930	23/105 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	349..415		8/22 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845948
Domainoid	1	1.000	70	1.000	Domainoid score	I9560
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2366
Inparanoid	1	1.050	178	1.000	Inparanoid score	I4018
Isobase	1	0.950	-	0	Normalized mean entropy	S2962
OMA	1	1.010	-	-		QHG54025
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002882
OrthoInspector	1	1.000	-	-		oto93301
orthoMCL	1	0.900	-	-		OOG6_102594
Panther	1	1.100	-	-	LDO	PTHR22792
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R649
SonicParanoid	1	1.000	-	-		X1665
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	14.880