DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10651 and vap-1

DIOPT Version :9

Sequence 1:	NP_001286095.1	Gene:	CG10651 / 35303	FlyBaseID:	FBgn0032853	Length:	316	Species:	Drosophila melanogaster
Sequence 2:	NP_001024553.1	Gene:	vap-1 / 181768	WormBaseID:	WBGene00006886	Length:	424	Species:	Caenorhabditis elegans

Alignment Length:	236	Identity:	55/236 - (23%)
Similarity:	89/236 - (37%)	Gaps:	67/236 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 CPKQAAAM------VKMSWDMIALIVDKHNEYRNKFAGGMDQNPKAARMT------TIEWDPEL- 97
            |.::|.|.      .|::.....:..|.||:.|...|.|::.| |...::      .:.||.|:
Worm    12 CLERAVAQTFGCSNTKINDQARKMFYDAHNDARRSMAKGLEPN-KCGLLSGGKNVYELNWDCEME 75

  Fly    98 AKV---ADGLVRRCEPIRDQCAITPNYGHAEVSYSLEKYFCMTTKKEAL---RKQLDHWF----- 151
            ||.   |||    | |...| ...|.:|....:|       |.:..:.|   ...::.|:
Worm    76 AKAQEWADG----C-PSSFQ-TFDPTWGQNYATY-------MGSIADPLPYASMAVNGWWSEIRT 127

  Fly   152 ----DPNSKDEVQKLFFSWTKNQQELSKNYFQVLRDRANRVGCAIVEYVRPALVHQLL--KCVYN 210
                ||::|.....:|            .:..:...:|:..|||.      ||....|  .|:||
Worm   128 VGLTDPDNKYTNSAMF------------RFANMANGKASAFGCAY------ALCAGKLSINCIYN 174

  Fly   211 CGVSLCEEEDNPVYEDTDE-EAASECMKGSNKQYKN-LCHK 249
               .:....:..:||..|. .:.:||...|:.|.|| ||:|
Worm   175 ---KIGYMTNAIIYEKGDACTSDAECTTYSDSQCKNGLCYK 212

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10651	NP_001286095.1	SCP_euk	61..210	CDD:240180	37/172 (22%)
vap-1	NP_001024553.1	SCP	31..175	CDD:214553	39/178 (22%)
vap-1	NP_001024553.1	SCP	234..386	CDD:214553
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920