Protein Alignment Kua and PEDS1-UBE2V1

DIOPT Version :9

• Sequence 1: NP_001188856.1
• Gene: Kua / 35300
• FlyBaseID: FBgn0032850
• Length: 310
• Species: Drosophila melanogaster
• Sequence 2: NP_954673.2
• Gene: PEDS1-UBE2V1 / 387522
• HGNCID: 33521
• Length: 370
• Species: Homo sapiens
• Alignment Length: 245
• Identity: 133/245 - (54%)
• Similarity: 165/245 - (67%)
• Gaps: 11/245 - (4%)

  Fly    63 RWGPQNKGAQELALLYSPGKRAQEIICVYTCIGLMIINLALIVRHLRLERISVAFLSALCGIITA 127
            |||.|:.||:|||.|||||||.||...|..|..|:..||..::...|.|...:..|..:.|.:.|
Human    23 RWGAQHAGARELAALYSPGKRLQEWCSVILCFSLIAHNLVHLLLLARWEDTPLVILGVVAGALIA 87

  Fly   128 DFASGLVHWAADTWGSVDIPMIGKNFLRPFREHHLDPTSITRHDFIETNGDNFMVG-IPILGYLA 191
            ||.||||||.|||||||::|::||.|:|||||||:|||:|||||||||||||.:|. :|:|. :|
Human    88 DFLSGLVHWGADTWGSVELPIVGKAFIRPFREHHIDPTAITRHDFIETNGDNCLVTLLPLLN-MA 151

  Fly   192 HYFYIRTPSEIQQHFGWIAYVFLCSIFVAMTNQIHKWSHTYWGLPRWVLLLQSCHIILPRKHHRI 256
            :.|...:|..::|.:.|..:||...||...|||||||||||:||||||.|||..|:|||||||||
Human   152 YKFRTHSPEALEQLYPWECFVFCLIIFGTFTNQIHKWSHTYFGLPRWVTLLQDWHVILPRKHHRI 216

  Fly   257 HHVAPHETYFCITTGWLNWPLERIRFWSTFELIIEHFTGLK-PRDDDLKW 305
            |||:|||||||||||        ::....|.|:.|...|.| ..|..:.|
Human   217 HHVSPHETYFCITTG--------VKVPRNFRLLEELEEGQKGVGDGTVSW 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kua	NP_001188856.1	TMEM189_B_dmain	124..301	CDD:287490	104/178 (58%)
PEDS1-UBE2V1	NP_954673.2	TMEM189_B_dmain	85..251	CDD:402241	104/174 (60%)
		UBCc	239..365	CDD:214562	6/20 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	260	1.000	Domainoid score	I1991
eggNOG	1	0.900	-	-		E1_KOG3011
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	321	1.000	Inparanoid score	I2528
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG56240
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003637
OrthoInspector	1	1.000	-	-		oto89802
orthoMCL	1	0.900	-	-		OOG6_104857
Panther	1	1.100	-	-	LDO	PTHR48177
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4428
SonicParanoid	1	1.000	-	-		X4054
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	13	12.860