DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Kua and Peds1

DIOPT Version :9

Sequence 1:	NP_001188856.1	Gene:	Kua / 35300	FlyBaseID:	FBgn0032850	Length:	310	Species:	Drosophila melanogaster
Sequence 2:	NP_001107224.1	Gene:	Peds1 / 362278	RGDID:	1309093	Length:	271	Species:	Rattus norvegicus

Alignment Length:	248	Identity:	147/248 - (59%)
Similarity:	180/248 - (72%)	Gaps:	2/248 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 RWGPQNKGAQELALLYSPGKRAQEIICVYTCIGLMIINLALIVRHLRLERISVAFLSALCGIITA 127
            |||.|:.||:|||.|||||||.||...|..|..|:..|...::...|.|...:..|..:.|.:.|
  Rat    24 RWGAQHAGARELAALYSPGKRLQEWCSVILCFSLIAHNSVHLLLLARWEHTPLVILGVVAGALVA 88

  Fly   128 DFASGLVHWAADTWGSVDIPMIGKNFLRPFREHHLDPTSITRHDFIETNGDNFMVG-IPILGYLA 191
            ||.||||||.||||||||:|::||.|:|||||||:|||:|||||||||||||.:|. :|:|. :|
  Rat    89 DFLSGLVHWGADTWGSVDLPIVGKAFIRPFREHHIDPTAITRHDFIETNGDNCLVTLLPLLN-MA 152

  Fly   192 HYFYIRTPSEIQQHFGWIAYVFLCSIFVAMTNQIHKWSHTYWGLPRWVLLLQSCHIILPRKHHRI 256
            :.|..::|..::|.:.|..:||...||...|||||||||||.|||.||.:||..|:|||||||||
  Rat   153 YKFQTQSPETLEQLYPWECFVFCLIIFGTFTNQIHKWSHTYLGLPCWVTVLQDWHVILPRKHHRI 217

  Fly   257 HHVAPHETYFCITTGWLNWPLERIRFWSTFELIIEHFTGLKPRDDDLKWAKKL 309
            ||||||||||||||||||:|||.|.||...|.:|:..||.|||.||:|||:|:
  Rat   218 HHVAPHETYFCITTGWLNYPLEVIGFWRRLEDVIQSLTGEKPRADDMKWAQKI 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Kua	NP_001188856.1	TMEM189_B_dmain	124..301	CDD:287490	115/177 (65%)
Peds1	NP_001107224.1	TMEM189_B_dmain	86..262	CDD:402241	115/176 (65%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	258	1.000	Domainoid score	I1938
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	290	1.000	Inparanoid score	I2715
OMA	1	1.010	-	-		QHG56240
OrthoDB	1	1.010	-	-		D1421561at2759
OrthoFinder	1	1.000	-	-		FOG0003637
OrthoInspector	1	1.000	-	-		oto96914
orthoMCL	1	0.900	-	-		OOG6_104857
Panther	1	1.100	-	-	LDO	PTHR48177
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4054
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	10.980