Protein Alignment APRT and APT1

DIOPT Version :10

• Sequence 1: NP_000476.1
• Gene: APRT / 353
• HGNCID: 626
• Length: 180
• Species: Homo sapiens
• Sequence 2: NP_013690.1
• Gene: APT1 / 854986
• SGDID: S000004484
• Length: 187
• Species: Saccharomyces cerevisiae
• Alignment Length: 175
• Identity: 84/175 - (48%)
• Similarity: 116/175 - (66%)
• Gaps: 7/175 - (4%)

Human     5 ELQLVEQRIRSFPDFPTPGVVFRDISPVLKDPASFRAAIGLLARHL-KATHGGRIDYIAGLDSRG 68
            ||:|.   :..:|:||:.|::|.|..|:.::|..|:..|.....|| :|....:||||.||:|||
Yeast     9 ELKLA---LHQYPNFPSEGILFEDFLPIFRNPGLFQKLIDAFKLHLEEAFPEVKIDYIVGLESRG 70

Human    69 FLFGPSLAQELGLGCVLIRKRGKLPGPTLWASYSLEYGKAELEIQKDALEPGQRVVVVDDLLATG 133
            |||||:||..||:|.|.:||.|||||....|:|..|||....||||:|:..|..|::|||::|||
Yeast    71 FLFGPTLALALGVGFVPVRKAGKLPGECFKATYEKEYGSDLFEIQKNAIPAGSNVIIVDDIIATG 135

Human   134 GTMNAACELLGRLQAEVLECVSLVELTSLKGREKL-APVPFFSLL 177
            |:..||.||:.:|:|.:||...::||..||||.|| |||  |:||
Yeast   136 GSAAAAGELVEQLEANLLEYNFVMELDFLKGRSKLNAPV--FTLL 178

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
APRT	NP_000476.1	apt	9..179	CDD:273437	81/171 (47%)
APT1	NP_013690.1	apt	10..180	CDD:273437	83/174 (48%)