Protein Alignment APRT and aprt

DIOPT Version :10

• Sequence 1: NP_000476.1
• Gene: APRT / 353
• HGNCID: 626
• Length: 180
• Species: Homo sapiens
• Sequence 2: NP_001007941.1
• Gene: aprt / 493317
• XenbaseID: XB-GENE-5848953
• Length: 180
• Species: Xenopus tropicalis
• Alignment Length: 181
• Identity: 114/181 - (62%)
• Similarity: 144/181 - (79%)
• Gaps: 2/181 - (1%)

Human     1 MADSEL-QLVEQRIRSFPDFPTPGVVFRDISPVLKDPASFRAAIGLLARHLKATHGGRIDYIAGL 64
            |:|.|. :::...||:|||||:||:.||||:||||||.:|.:.|.|..:||:|.. .:||.||||
 Frog     1 MSDQEKEEIIRTAIRAFPDFPSPGICFRDITPVLKDPLAFCSVIDLFEKHLRANF-PKIDVIAGL 64

Human    65 DSRGFLFGPSLAQELGLGCVLIRKRGKLPGPTLWASYSLEYGKAELEIQKDALEPGQRVVVVDDL 129
            |||||||||||||...:|.:||||:|||||||...||||||||||||:|.||:||||:||::|||
 Frog    65 DSRGFLFGPSLAQRFNIGFLLIRKKGKLPGPTESVSYSLEYGKAELEMQYDAVEPGQKVVLIDDL 129

Human   130 LATGGTMNAACELLGRLQAEVLECVSLVELTSLKGREKLAPVPFFSLLQYE 180
            |||||||||||||:.|..||:|:|:.::||.||||.:|:.|....|||||:
 Frog   130 LATGGTMNAACELVKRRNAEILDCLVVIELKSLKGAQKIKPYTVHSLLQYD 180

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
APRT	NP_000476.1	apt	9..179	CDD:273437	109/169 (64%)
aprt	NP_001007941.1	PRK02304	5..180	CDD:235028	111/175 (63%)