Protein Alignment APRT and Aprt

DIOPT Version :10

• Sequence 1: NP_000476.1
• Gene: APRT / 353
• HGNCID: 626
• Length: 180
• Species: Homo sapiens
• Sequence 2: NP_476637.1
• Gene: Aprt / 48224
• FlyBaseID: FBgn0000109
• Length: 182
• Species: Drosophila melanogaster
• Alignment Length: 178
• Identity: 82/178 - (46%)
• Similarity: 116/178 - (65%)
• Gaps: 2/178 - (1%)

Human     2 ADSELQLVEQRIRSFPDFPTPGVVFRDISPVLKDPASFRAAIGLLARHLKATHGGRIDYIAGLDS 66
            |:.:|..|:.:|..:|:||..|::||||...|.||.:......||..|::.: ....:.|.||||
  Fly     7 AEDKLDYVKSKIGEYPNFPKEGILFRDIFGALTDPKACVYLRDLLVDHIRES-APEAEVIVGLDS 70

Human    67 RGFLFGPSLAQELGLGCVLIRKRGKLPGPTLWASYSLEYGKAELEIQKDALEPGQRVVVVDDLLA 131
            |||||...:|.||||||..|||:|||.|..:...|.||||....|:||.|::|||:|||||||||
  Fly    71 RGFLFNLLIATELGLGCAPIRKKGKLAGEVVSVEYKLEYGIDTFELQKSAIKPGQKVVVVDDLLA 135

Human   132 TGGTMNAACELLGRLQAEVLECVSLVELTSLKGREKLAPVPFFSLLQY 179
            |||::.||.||:|::...|:|.:.::||..|:||::| .....||::|
  Fly   136 TGGSLVAATELIGKVGGVVVESLVVMELVGLEGRKRL-DGKVHSLIKY 182

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
APRT	NP_000476.1	apt	9..179	CDD:273437	79/169 (47%)
Aprt	NP_476637.1	PRK02304	9..182	CDD:235028	80/174 (46%)