DRSC/TRiP Functional Genomics Resources

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Protein Alignment APRT and apt1

DIOPT Version :10

Sequence 1:NP_000476.1 Gene:APRT / 353 HGNCID:626 Length:180 Species:Homo sapiens
Sequence 2:NP_594433.1 Gene:apt1 / 2542022 PomBaseID:SPAC23A1.03 Length:188 Species:Schizosaccharomyces pombe


Alignment Length:177 Identity:78/177 - (44%)
Similarity:113/177 - (63%) Gaps:2/177 - (1%)


- Green bases have known domain annotations that are detailed below.


Human     1 MADSELQLVEQRIRSFPDFPTPGVVFRDISPVLKDPASFRAAIGLLARHLKATHGGRIDYIAGLD 65
            |:|..:..::.::..:||||..|::|.||.|:.:||.:|...|.||...:: |....||.|.||:
pombe     1 MSDDRINYLKNKLVQYPDFPKKGILFEDIMPIFQDPRAFGILIDLLLEAVE-TEFNNIDVIVGLE 64

Human    66 SRGFLFGPSLAQELGLGCVLIRKRGKLPGPTLWASYSLEYGKAELEIQKDALEPGQRVVVVDDLL 130
            :|||||||:||.......|.:||..||||..:..||:.||......|||..::|||||::|||:|
pombe    65 ARGFLFGPTLALRANCAFVPVRKPNKLPGDLVVVSYNKEYSTDSFAIQKGTIKPGQRVLIVDDIL 129

Human   131 ATGGTMNAACELLGRLQAEVLECVSLVELTSLKGREKLAPVPFFSLL 177
            |||||..||.||:.||..|::..:.|:|||.|:||::|. .|.::||
pombe   130 ATGGTALAADELVTRLGGELVGHLFLLELTFLQGRKRLM-APTYTLL 175

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
APRTNP_000476.1 apt 9..179 CDD:273437 76/169 (45%)
apt1NP_594433.1 PRK02304 8..176 CDD:235028 76/170 (45%)

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