Protein Alignment APRT and aprt-1

DIOPT Version :10

• Sequence 1: NP_000476.1
• Gene: APRT / 353
• HGNCID: 626
• Length: 180
• Species: Homo sapiens
• Sequence 2: NP_491663.1
• Gene: aprt-1 / 172232
• WormBaseID: WBGene00020557
• Length: 185
• Species: Caenorhabditis elegans
• Alignment Length: 172
• Identity: 79/172 - (45%)
• Similarity: 112/172 - (65%)
• Gaps: 1/172 - (0%)

Human     9 VEQRIRSFPDFPTPGVVFRDISPVLKDPASFRAAIGLLARHLKATHGGRIDYIAGLDSRGFLFGP 73
            :||.||...|||..|:.||||.|:..:|........::|.|::.| .|.:|.:|||::|||||||
 Worm    13 IEQHIREVKDFPKKGINFRDIMPLFTNPQLVNELCVVIADHVRHT-VGHVDSVAGLEARGFLFGP 76

Human    74 SLAQELGLGCVLIRKRGKLPGPTLWASYSLEYGKAELEIQKDALEPGQRVVVVDDLLATGGTMNA 138
            .:|.:||:..|.|||:|||||.|:.|||..|||:..:|||:.|::.|..|.::|||||||||:.|
 Worm    77 QVAIQLGVPFVPIRKKGKLPGATIEASYVKEYGEDRVEIQEGAIKNGDIVFLIDDLLATGGTLRA 141

Human   139 ACELLGRLQAEVLECVSLVELTSLKGREKLAPVPFFSLLQYE 180
            |.:|:.:...:|.|...|:||..|.||.||..|...:|:.|:
 Worm   142 ATDLVVKAGGKVGEAFVLIELAPLNGRSKLPDVNLTTLISYD 183

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
APRT	NP_000476.1	apt	9..179	CDD:273437	78/169 (46%)
aprt-1	NP_491663.1	PRK02304	12..183	CDD:235028	78/170 (46%)