Protein Alignment nesd and Shcbp1l

DIOPT Version :9

• Sequence 1: NP_610025.1
• Gene: nesd / 35298
• FlyBaseID: FBgn0032848
• Length: 602
• Species: Drosophila melanogaster
• Sequence 2: NP_001028334.1
• Gene: Shcbp1l / 71836
• MGIID: 1919086
• Length: 639
• Species: Mus musculus
• Alignment Length: 614
• Identity: 132/614 - (21%)
• Similarity: 229/614 - (37%)
• Gaps: 180/614 - (29%)

  Fly    11 LERLKEAEAVLSWEGAVMPASQVRSEWKSYVEL---KIEPAGWQAIWKIPRVICEDLKLRYPTIV 72
            ||:||..:   .|.|.          |||..||   |.|.|....:..:..|.|:..:
Mouse   134 LEKLKAKD---RWLGV----------WKSNPELFFEKYEEASIPFVGILVEVTCKPRQ------- 178

  Fly    73 YGYVEQVIFDELKAVFVVTAVQDSDVHLPESNEVS-------------------LVELWPTVQQE 118
                      .|.:.|.||.    .|..|.|:.::                   |:|::|...|:
Mouse   179 ----------NLSSCFKVTV----SVAEPFSSNIANIPRDLVDEVLGELEYSAPLLEVYPVDGQD 229

  Fly   119 NAALNVDTTAECIDRLRFFYTHVWMPWDKDYDDDRDWVQQHLQARIQLVCDLSKNRLPRPLALHM 183
               .:|...|..::.:||||..:|..|| |.::..::... ::.||.|.||:....:|.|:|...
Mouse   230 ---ADVRDIALALEVVRFFYDFLWRDWD-DEENCENYTAL-IEERINLWCDIQDGTIPGPIAQRF 289

  Fly   184 RTLLAEAKYIQQRLDYLELDLSDAESDDEAVELNDSVAEPARKQSKAGSANGCLNVSSLPVTDLM 248
            :..|  .||..:|::.:|.. |:.:.|..|.|    ..|..:|..:.....|.|.         |
Mouse   290 KKTL--EKYKNKRVELIEYQ-SNIKEDPSAAE----AVECWKKYYEIVMLCGLLK---------M 338

  Fly   249 CLHLRMAIIRSEF-EILENPEMRRAYSELQSNSLKRLRCSSGRTRQSEDLLVERNSISHVVTLPG 312
            ...||:.:....| .||...:.:|.:               |:|            |:|:|.
Mouse   339 WEDLRLRVHGPFFPRILRRRKGKRDF---------------GKT------------ITHIVA--- 373

  Fly   313 KLQQQLELLKLAQT-LVK---PESKVQLSNTLQDVLSICQSNDDILLSPGEHTIKFLEHLNDNGS 373
                     |:..| :||   .::.:|..|.|...|..|.|.|.:::.|||:....|..|.|:.:
Mouse   374 ---------KVMTTDMVKNLSSDTLLQQHNDLNLALDSCYSGDIVVIFPGEYQASNLALLTDDIT 429

  Fly   374 LRGLTQPEAILSPAADLSLLPVVCSSDEDSTLLVIDGDYTLSELVLDCRHVRRG-----ILLRNG 433
            ::|:.:.|.|:          :......||.::....:..|.:|.|    :::|     :::.:|
Mouse   430 IKGVGKREEIM----------ITSEPSHDSFVVSKADNVKLMQLSL----IQQGTVDGIVVVESG 480

  Fly   434 TLTMRGCRLLGDGSSSTQEGIVCMPGASVELKSCLIENF-AVGVSMRPKSSAELGSVQFKTCKTG 497
            .||:..|.|..:|:     |:..:.|||:.:.:..|... ..||.:.|.|.|.|...:...| ..
Mouse   481 HLTLENCLLKCEGT-----GVCVLTGASLTITNSEITGAQGAGVELYPGSIAILEGNEIHHC-NN 539

  Fly   498 LELLEKSAS----VNLQ---------GSKCSFENCALGI----------------LADGFVLGEQ 533
            |...:.|.|    ||::         .:...:.|...|:                |..|...|::
Mouse   540 LRTSDSSKSTLGGVNMKVLPAPKLKMTNNHIYNNNGYGVSILQPSEQFFIVAEAALNKGAASGDK 604

  Fly   534 RTEKVL--VLNKFSELQRYN--EDNLLGN 558
            :.:|:|  |:...:.....|  |.||.|:
Mouse   605 KDDKMLSKVMQTLNVEMNNNRIEANLKGD 633

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nesd	NP_610025.1	None
Shcbp1l	NP_001028334.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..25
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	48..75
		Beta_helix	472..>580	CDD:289971	25/113 (22%)
		PbH1 1	479..500		7/25 (28%)
		Beta_helix	495..>639	CDD:289971	30/140 (21%)
		PbH1 2	501..523		6/21 (29%)
		PbH1 3	524..557		9/33 (27%)
		PbH1 4	560..582		2/21 (10%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	104	1.000	Inparanoid score	I4931
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005693
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR14695
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	6.020